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Functional and structural analyses reveal that a dual domain sialidase protects bacteria from complement killing through desialylation of complement factors
The complement system is the first line of innate immune defense against microbial infections. To survive in humans and cause infections, bacterial pathogens have developed sophisticated mechanisms to subvert the complement-mediated bactericidal activity. There are reports that sialidases, also know...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553830/ https://www.ncbi.nlm.nih.gov/pubmed/37747935 http://dx.doi.org/10.1371/journal.ppat.1011674 |