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The clinical value of hsa-miR-190b-5p in peripheral blood of pediatric β-thalassemia and its regulation on BCL11A expression

BACKGROUND: The B cell CLL/lymphoma 11A (BCL11A) is a key regulator of hemoglobin switching in β-thalassemia (β-thal). Previous study has suggested that dysregulated microRNAs are involved in the regulation of BCL11A expression. The aim of this study was to investigate the clinical value of hsa-miR-...

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Detalles Bibliográficos
Autores principales:	Chen, Meihuan, Wang, Xinrui, Wang, Haiwei, Zhang, Min, Chen, Lingji, Chen, Hong, Pan, Yali, Zhang, Yanhong, Xu, Liangpu, Huang, Hailong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553837/ https://www.ncbi.nlm.nih.gov/pubmed/37796993 http://dx.doi.org/10.1371/journal.pone.0292031

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