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OR19-01 Srd5a1 Undergoes Distinct Changes in Methylation and Is Differentially Expressed During Pre-Pubertal Development in the Ovary and Hypothalamus

Disclosure: B. Bar-Sadeh: None. P. Melamed: None. The steroidogenic enzyme, 5α-reductase-1, is responsible for conversion of testosterone to dihydrotestosterone, and production of other 5α-reduced steroids and their derivatives, including in the brain. We reported previously that Srd5a1 levels are r...

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Detalles Bibliográficos
Autores principales: Bar-Sadeh, Ben, Melamed, Philippa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553891/
http://dx.doi.org/10.1210/jendso/bvad114.1647