Cargando…

OR0304 Novel Dual Antagonists Of The Growth Hormone Receptor And The Prolactin Receptor

Disclosure: R. Basu: None. J.J. Kopchick: None. An excess of the human growth hormone (hGH) is associated with multiple pathophysiology including acromegaly, diabetes, cancer, renal dysfunction and age-associated cognitive impairment. On the other hand, a congenital lack of GH action in humans and m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Basu, Reetobrata, Kopchick, John Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Neuroendocrinology & Pituitary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10554297/ http://dx.doi.org/10.1210/jendso/bvad114.1206

Ejemplares similares

MON-476 Growth Hormone and the Glomerular Podocyte: Studies of Podocyte-Specific Growth Hormone Receptor Gene Deletion in Mice
por: Brittain, Alison, et al.
Publicado: (2019)

A Novel Peptide Antagonist of the Human Growth Hormone Receptor
por: Basu, Reetobrata None, et al.
Publicado: (2021)

SAT-283 Generation of a Long-Acting Human Growth Hormone Receptor Antagonist by Site-Specific Pegylation
por: Wang, Yue, et al.
Publicado: (2020)

FRI318 A Case Of Mixed Growth Hormone And Prolactin-secreting Giant Pituitary Macroadenoma
por: Khan, Aysha, et al.
Publicado: (2023)

Structure and function of a dual antagonist of the human growth hormone and prolactin receptors with site-specific PEG conjugates
por: Basu, Reetobrata, et al.
Publicado: (2023)

THU048 Determination Of Receptor Binding Affinity Of Growth Hormone Analogues To The Growth Hormone Receptor In A Drug Screening Context
por: Erlendsson, Simon, et al.
Publicado: (2023)

The Effect of the Synergy Between Opiates and Prolactin on the Growth of Chickens
por: Abdulateef, Salwan M, et al.
Publicado: (2021)

SAT-LB081 Growth Hormone and Prolactin Secreting Plurihormonal Pituitary Adenomas, Experience of a National Health Institute in Mexico
por: Guzmán-Pérez, Alberto, et al.
Publicado: (2019)

MON-479 Gross and Microscopic Intestinal Morphology of Bovine Growth Hormone Transgenic Mice Longitudinally
por: Young, Jonathan, et al.
Publicado: (2019)

SUN-LB51 Growth Hormone Deficiency and Resistance Result in Altered Intestinal Gross Anatomy and Morphology in Mice at Adult and Older Adult Timepoints
por: Kuhn, Jaycie J, et al.
Publicado: (2020)

SAT-281 Chronic, Excess Growth Hormone Action Alters the Development and Aging of the Microbial Community in the Mouse Gut
por: Jensen, Elizabeth Ann, et al.
Publicado: (2020)

THU545 Growth Hormone Receptor Antagonist As A Novel Combination Therapy Against Triple Negative Breast Cancer
por: Mora-Criollo, Patricia, et al.
Publicado: (2023)

THU046 Repeated Treatment With AZP-3813, A Bicyclic, 16-Amino Acid Peptide Antagonist Of The Human Growth Hormone Receptor, Induces Enhanced Suppression Of IGF1 In Beagle Dogs
por: Ravel, Guillaume, et al.
Publicado: (2023)

ODP353 Sustained Suppression of IGF1 with AZP-3813, a Bicyclic 16-Amino Acid Peptide Antagonist of the Human Growth Hormone Receptor and a Potential New Treatment for Acromegaly
por: Culler, Michael, et al.
Publicado: (2022)

MON-473 Growth Hormone (GH) Impacts the Gut Microbial Profile: the Presence of Unique Bacterial Genera in Mouse Lines with Altered GH Action
por: Jensen, Elizabeth, et al.
Publicado: (2019)

Expression of IGF-1, IGF-1 Receptor and Growth Hormone Receptor in Hepatic Tissue in Adults Across the Spectrum of Nonalcoholic Fatty Liver Disease (NAFLD)
por: Dichtel, Laura E, et al.
Publicado: (2021)

SUN-LB58 Repeated Once-Daily Administration of the Non-Hormonal Neurokinin 1,3 Receptor Antagonist NT-814 Reduces LH, Estradiol and Progesterone in Healthy Women
por: Dhillo, Waljit Singh, et al.
Publicado: (2020)

MON-434 Familial Alactogenesis Associated with a Prolactin Mutation
por: Moriwaki, Mika, et al.
Publicado: (2019)

OR01-04 The Growth Hormone Receptor Interacts With Transcriptional Regulator, HMGN1, Upon GH-induced Nuclear Translocation
por: Jain, Lekha, et al.
Publicado: (2023)

A novel peptide antagonist of the human growth hormone receptor
por: Basu, Reetobrata, et al.
Publicado: (2021)

Discordance Between Prolactinoma Size and Prolactin Level: An Unusual Laboratory Finding
por: Dawaher, Wafa, et al.
Publicado: (2021)

TSH, GH, and Prolactin Producing Pituitary Adenoma: An Unusual Case Presentation
por: Manrique, Helard Andres, et al.
Publicado: (2021)

PMON129 Pituitary Adenoma Co-Secreting GH, Prolactin and ACTH
por: Wilson, Sarah, et al.
Publicado: (2022)

PMON106 Persistent Prolactin Levels in a Patient with Pituitary Adenoma
por: Kadakia, Natasha, et al.
Publicado: (2022)

Neuromedin B Receptor Antagonist Suppresses Pomc Expression in AtT-20 Cells and Human Corticotroph Adenoma Cells
por: Sekizaki, Tomonori, et al.
Publicado: (2021)

ODP343 Phoenixin as a Novel Autocrine/Paracrine Factor Stimulating Prolactin Secretion and Gene Expression at the Pituitary Level in Fish Model
por: Wong, Anderson O L, et al.
Publicado: (2022)

SAT-240 Hypothalamic Lipoma and Growth Hormone Deficiency
por: Rochtus, Anne Maria, et al.
Publicado: (2020)

FRI301 Prolactin And Obesity: Analysis Off Weight Oscillation In The Follow-up Of Macroprolactinomas
por: Oliveira, Miriam C, et al.
Publicado: (2023)

MON-486 Prolactin Reduces the Hyperoxia-Induced Inhibition of Retinal Neovascularization in Newborn Mice
por: Vazquez-Membrillo, Miguel, et al.
Publicado: (2019)

MON-272 Clinical Relevance of Serum Prolactin Levels to Inflammatory Reaction in Male Patients
por: Yamamoto, Koichiro, et al.
Publicado: (2020)

THU020 Bilateral Adrenal Hyperplasia (BAH): Undesirable Effect Of Glucocorticoid Receptor Competitive Antagonist (GRCAnt) In Cushing’s Disease
por: Canturk, Ayse, et al.
Publicado: (2023)

ODP338 Neuromedin B Receptor Antagonist Suppresses ACTH Secretion and Cell Proliferation in Human and Mouse Corticotroph Adenoma
por: Atsumi, Tatsuya, et al.
Publicado: (2022)

FRI295 Prolactin Exerts Anti- And Pro-inflammatory Actions In Joint Tissues That Are Cytokine-Dependent
por: García Rodrigo, José Fernando, et al.
Publicado: (2023)

OR06-3 Prolactin Acts on Glutamatergic Neurons in the Ventromedial Nucleus of the Hypothalamus to Modulate Maternal Aggression
por: Barad, Zsuzsanna, et al.
Publicado: (2019)

MON-275 Prolactin to Testosterone Ratio Predicts Pituitary Pathology in Hypogonadal Men with Mild Hyperprolactinemia
por: Naelitz, Bryan D, et al.
Publicado: (2020)

MON-281 A Pilot Study: Comparing Prolactin Measurements Between Two Different Immunoassays
por: Woznick, Walter K, et al.
Publicado: (2020)

MON-LB60 Prolactin Response to Metformin in Cabergoline-Resistant Prolactinomas: A Prospective Study
por: Corrêa Portari, Luiz Henrique, et al.
Publicado: (2020)

PMON109 A Case of Non-functioning Pituitary Adenoma With Unexpectedly High Prolactin Level
por: Mahali, Lakshmi Priyanka, et al.
Publicado: (2022)

THU050 The Role Of The GH Receptor Polymorphism As Prognostic Factor Of Vertebral Fractures In Acromegaly Patients Resistant To First Generation SSAs And Treated With GH Receptor Antagonist Or Second Generation Somatostatin Ligand
por: Costanza, Flavia, et al.
Publicado: (2023)

Differential Expression of Estrogen Receptors in the Hypothalamus Underlies the Bimodal Effects of Estradiol on Luteinizing Hormone Release
por: Henriques, Patricia Costa, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ua6ja9bk8fug1kbi1blhdrpeso