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THU547 Role Of NAD(+) Synthesis Pathway In PARP Inhibitor Resistance

Disclosure: S. Challa: None. ADP-ribosylation is catalyzed by the poly(ADP-ribose) polymerase (PARP) family of enzymes consisting of 17 members that have distinct structural domains, activities, subcellular localizations, and functions. The catalytic activities of PARP enzymes are intimately tied to...

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Detalles Bibliográficos
Autores principales: Myong, Subin, Challa, Sridevi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555302/
http://dx.doi.org/10.1210/jendso/bvad114.2173

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