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Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF-κB and MAPK signalling transduction through integrin αVβ3

Osteoarthritis (OA) is a chronic progressive articular illness which commonly affects older-aged adults, presenting with cartilage inflammation and degradation. Rutaecarpine (RUT) has been shown to exert promising anti-inflammatory effects; however, the efficacy of RUT in the treatment of OA is deba...

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Detalles Bibliográficos
Autores principales: Wan, Junlai, Li, Mengwei, Yuan, Xi, Yu, Xiaojun, Chen, Anmin, Shao, Ming, Kang, Hao, Cheng, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555473/
https://www.ncbi.nlm.nih.gov/pubmed/37654229
http://dx.doi.org/10.3892/ijmm.2023.5300