Cargando…

Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF-κB and MAPK signalling transduction through integrin αVβ3

Osteoarthritis (OA) is a chronic progressive articular illness which commonly affects older-aged adults, presenting with cartilage inflammation and degradation. Rutaecarpine (RUT) has been shown to exert promising anti-inflammatory effects; however, the efficacy of RUT in the treatment of OA is deba...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wan, Junlai, Li, Mengwei, Yuan, Xi, Yu, Xiaojun, Chen, Anmin, Shao, Ming, Kang, Hao, Cheng, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555473/ https://www.ncbi.nlm.nih.gov/pubmed/37654229 http://dx.doi.org/10.3892/ijmm.2023.5300

Ejemplares similares

Physalin A Inhibits MAPK and NF-κB Signal Transduction Through Integrin αVβ3 and Exerts Chondroprotective Effect
por: Lu, Rui, et al.
Publicado: (2021)

Targeting MAPK/NF-κB Pathways in Anti-Inflammatory Potential of Rutaecarpine: Impact on Src/FAK-Mediated Macrophage Migration
por: Jayakumar, Thanasekaran, et al.
Publicado: (2021)

IGF-1 Facilitates Cartilage Reconstruction by Regulating PI3K/AKT, MAPK, and NF-kB Signaling in Rabbit Osteoarthritis
por: Hossain, Mohammad Amjad, et al.
Publicado: (2021)

Promising derivatives of rutaecarpine with diverse pharmacological activities
por: Li, Deping, et al.
Publicado: (2023)

Progress in the Studies on Rutaecarpine
por: Lee, Seung Ho, et al.
Publicado: (2008)

Mulberroside A alleviates osteoarthritis via restoring impaired autophagy and suppressing MAPK/NF-κB/PI3K-AKT-mTOR signaling pathways
por: Lu, Rui, et al.
Publicado: (2023)

Targeting PI3K/Akt signal transduction for cancer therapy
por: He, Yan, et al.
Publicado: (2021)

Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-κB pathways
por: Lu, Jiansen, et al.
Publicado: (2021)

Rutaecarpine Ameliorates Pressure Overload Cardiac Hypertrophy by Suppression of Calcineurin and Angiotensin II
por: Li, Shujun, et al.
Publicado: (2021)

Cepharanthine Ameliorates Chondrocytic Inflammation and Osteoarthritis via Regulating the MAPK/NF-κB-Autophagy Pathway
por: Yao, Minjun, et al.
Publicado: (2022)

PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia
por: Xie, Youbang, et al.
Publicado: (2019)

Rutaecarpine Inhibits Doxorubicin-Induced Oxidative Stress and Apoptosis by Activating AKT Signaling Pathway
por: Liao, Zi-Qi, et al.
Publicado: (2022)

Inhibitory effects of delphinidin on the proliferation of ovarian cancer cells via PI3K/AKT and ERK 1/2 MAPK signal transduction
por: Lim, Whasun, et al.
Publicado: (2017)

Arctigenin prevents the progression of osteoarthritis by targeting PI3K/Akt/NF‐κB axis: In vitro and in vivo studies
por: Tang, Shangkun, et al.
Publicado: (2020)

Maltol prevents the progression of osteoarthritis by targeting PI3K/Akt/NF‐κB pathway: In vitro and in vivo studies
por: Lu, Hongwei, et al.
Publicado: (2020)

Gelidium elegans Extract Ameliorates Type 2 Diabetes via Regulation of MAPK and PI3K/Akt Signaling
por: Choi, Jia, et al.
Publicado: (2018)

Antitumor Activity of Tenacissoside H on Esophageal Cancer through Arresting Cell Cycle and Regulating PI3K/Akt-NF-κB Transduction Cascade
por: Jia, Yong-sen, et al.
Publicado: (2015)

Schisandrin B ameliorated chondrocytes inflammation and osteoarthritis via suppression of NF-κB and MAPK signal pathways
por: Ran, Jisheng, et al.
Publicado: (2018)

Fengshi Gutong Capsule Attenuates Osteoarthritis by Inhibiting MAPK, NF-κB, AP-1, and Akt Pathways
por: Gao, Yao-Xin, et al.
Publicado: (2018)

Mycobacterial Heparin-binding Hemagglutinin Antigen Activates Inflammatory Responses through PI3-K/Akt, NF-κB, and MAPK Pathways
por: Kim, Ki-Hye, et al.
Publicado: (2011)

Eupafolin induces apoptosis and autophagy of breast cancer cells through PI3K/AKT, MAPKs and NF-κB signaling pathways
por: Wei, Jiahui, et al.
Publicado: (2021)

Regulation of mRNA export by the PI3 kinase/AKT signal transduction pathway
por: Quaresma, Alexandre Jose Christino, et al.
Publicado: (2013)

Atractylenolide III ameliorated reflux esophagitis via PI3K/AKT/NF-κB/iNOS pathway in rats
por: Si, Xianzhe, et al.
Publicado: (2023)

Integrin αIIb-Mediated PI3K/Akt Activation in Platelets
por: Niu, Haixia, et al.
Publicado: (2012)

Integrin signal transduction
por: Leslie, Mitch
Publicado: (2006)

Time effect of rutaecarpine on caffeine pharmacokinetics in rats
por: Estari, Rohit Kumar, et al.
Publicado: (2021)

PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
por: Glaviano, Antonino, et al.
Publicado: (2023)

Thrombospondin 2 Promotes IL-6 Production in Osteoarthritis Synovial Fibroblasts via the PI3K/AKT/NF-κB Pathway
por: Hou, Chun-Han, et al.
Publicado: (2021)

Baicalin ameliorates APEC-induced intestinal injury in chicks by inhibiting the PI3K/AKT-mediated NF-κB signaling pathway
por: Cheng, Xinyi, et al.
Publicado: (2021)

Qizhi Kebitong Formula Ameliorates Streptozocin-Induced Diabetic Osteoporosis through Regulating the PI3K/Akt/NF-κB Pathway
por: Tian, Lulu, et al.
Publicado: (2022)

The Role of PI3K/AKT and MAPK Signaling Pathways in Erythropoietin Signalization
por: Tóthová, Zuzana, et al.
Publicado: (2021)

Antiproliferative Activity and Cellular Uptake of Evodiamine and Rutaecarpine Based on 3D Tumor Models
por: Guo, Hui, et al.
Publicado: (2016)

Rutaecarpine suppresses the proliferation and metastasis of colon cancer cells by regulating the STAT3 signaling
por: Chan, Shixin, et al.
Publicado: (2022)

Retraction Note: Eupafolin induces apoptosis and autophagy of breast cancer cells through PI3K/AKT, MAPKs and NF-κB signaling pathways
por: Wei, Jiahui, et al.
Publicado: (2021)

Boeravinone B, a natural rotenoid, inhibits osteoclast differentiation through modulating NF-κB, MAPK and PI3K/Akt signaling pathways
por: Piao, Xianyu, et al.
Publicado: (2023)

Maltol ameliorates intervertebral disc degeneration through inhibiting PI3K/AKT/NF-κB pathway and regulating NLRP3 inflammasome-mediated pyroptosis
por: Gong, Yuhang, et al.
Publicado: (2022)

Jiangtang decoction ameliorate diabetic nephropathy through the regulation of PI3K/Akt-mediated NF-κB pathways in KK-Ay mice
por: Hong, Jin-Ni, et al.
Publicado: (2017)

Phyllanthus Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NFκB, and Hypoxia)
por: Tang, Yin-Quan, et al.
Publicado: (2013)

Enhanced transdermal delivery of evodiamine and rutaecarpine using microemulsion
por: Zhang, Yong-Tai, et al.
Publicado: (2011)

Neuroprotective effects of rutaecarpine on cerebral ischemia reperfusion injury
por: Yan, Chunlin, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_hnd1s7eet2hpmt97qpj1fhvkg2