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Dyslipidemia in Patients with Chronic Kidney Disease: An Updated Overview
Dyslipidemia is a potentially modifiable cardiovascular risk factor. Whereas the recommendations for the treatment target of dyslipidemia in the general population are being more and more rigorous, the 2013 Kidney Disease: Improving Global Outcomes clinical practice guideline for lipid management in...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Diabetes Association
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555535/ https://www.ncbi.nlm.nih.gov/pubmed/37482655 http://dx.doi.org/10.4093/dmj.2023.0067 |
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author | Suh, Sang Heon Kim, Soo Wan |
author_facet | Suh, Sang Heon Kim, Soo Wan |
author_sort | Suh, Sang Heon |
collection | PubMed |
description | Dyslipidemia is a potentially modifiable cardiovascular risk factor. Whereas the recommendations for the treatment target of dyslipidemia in the general population are being more and more rigorous, the 2013 Kidney Disease: Improving Global Outcomes clinical practice guideline for lipid management in chronic kidney disease (CKD) presented a relatively conservative approach with respect to the indication of lipid lowering therapy and therapeutic monitoring among the patients with CKD. This may be largely attributed to the lack of high-quality evidence derived from CKD population, among whom the overall feature of dyslipidemia is considerably distinctive to that of general population. In this review article, we cover the characteristic features of dyslipidemia and impact of dyslipidemia on cardiovascular outcomes in patients with CKD. We also review the current evidence on lipid lowering therapy to modify the risk of cardiovascular events in this population. We finally discuss the association between dyslipidemia and CKD progression and the potential strategy to delay the progression of CKD in relation to lipid lowering therapy. |
format | Online Article Text |
id | pubmed-10555535 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Korean Diabetes Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-105555352023-10-07 Dyslipidemia in Patients with Chronic Kidney Disease: An Updated Overview Suh, Sang Heon Kim, Soo Wan Diabetes Metab J Review Dyslipidemia is a potentially modifiable cardiovascular risk factor. Whereas the recommendations for the treatment target of dyslipidemia in the general population are being more and more rigorous, the 2013 Kidney Disease: Improving Global Outcomes clinical practice guideline for lipid management in chronic kidney disease (CKD) presented a relatively conservative approach with respect to the indication of lipid lowering therapy and therapeutic monitoring among the patients with CKD. This may be largely attributed to the lack of high-quality evidence derived from CKD population, among whom the overall feature of dyslipidemia is considerably distinctive to that of general population. In this review article, we cover the characteristic features of dyslipidemia and impact of dyslipidemia on cardiovascular outcomes in patients with CKD. We also review the current evidence on lipid lowering therapy to modify the risk of cardiovascular events in this population. We finally discuss the association between dyslipidemia and CKD progression and the potential strategy to delay the progression of CKD in relation to lipid lowering therapy. Korean Diabetes Association 2023-09 2023-07-24 /pmc/articles/PMC10555535/ /pubmed/37482655 http://dx.doi.org/10.4093/dmj.2023.0067 Text en Copyright © 2023 Korean Diabetes Association https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Suh, Sang Heon Kim, Soo Wan Dyslipidemia in Patients with Chronic Kidney Disease: An Updated Overview |
title | Dyslipidemia in Patients with Chronic Kidney Disease: An Updated Overview |
title_full | Dyslipidemia in Patients with Chronic Kidney Disease: An Updated Overview |
title_fullStr | Dyslipidemia in Patients with Chronic Kidney Disease: An Updated Overview |
title_full_unstemmed | Dyslipidemia in Patients with Chronic Kidney Disease: An Updated Overview |
title_short | Dyslipidemia in Patients with Chronic Kidney Disease: An Updated Overview |
title_sort | dyslipidemia in patients with chronic kidney disease: an updated overview |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555535/ https://www.ncbi.nlm.nih.gov/pubmed/37482655 http://dx.doi.org/10.4093/dmj.2023.0067 |
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