Brain metastasis and intracranial leptomeningeal metastasis from malignant peripheral nerve sheath tumors: illustrative cases

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft-tissue tumors. Intracranial metastasis from MPNSTs is quite rare. OBSERVATIONS: The authors report on a 73-year-old male whose MPNST metastasized to the brain and a 32-year-old male with leptomeningeal metastasis from MPNST...

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Detalles Bibliográficos
Autores principales: Ohno, Masasuke, Haimoto, Shoichi, Tsukushi, Satoshi, Hosoda, Waki, Ohka, Fumiharu, Saito, Ryuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2023
Materias:
Case Lesson
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555573/
https://www.ncbi.nlm.nih.gov/pubmed/37486899
http://dx.doi.org/10.3171/CASE23148
Descripción
Sumario:BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft-tissue tumors. Intracranial metastasis from MPNSTs is quite rare. OBSERVATIONS: The authors report on a 73-year-old male whose MPNST metastasized to the brain and a 32-year-old male with leptomeningeal metastasis from MPNST and review 41 cases of MPNST that developed intracranial metastasis, as reported in the literature. LESSONS: Brain metastasis and leptomeningeal metastasis of MPNSTs show different clinical courses and require pathology-specific treatment.

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