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THU175 Incorrect Age Causing Falsely Short Stature In An Afghan Immigrant Girl

Disclosure: J. Ing: None. M. Marinkovic: None. Background: Evaluation for short stature routinely includes screening for hormone deficiencies, chromosomal abnormalities, gastroenterological diseases, and inflammatory processes. “Incorrect age” resulting in falsely short stature, is not often conside...

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Autores principales: Ing, Jordan, Marinkovic, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555736/
http://dx.doi.org/10.1210/jendso/bvad114.1426
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author Ing, Jordan
Marinkovic, Maja
author_facet Ing, Jordan
Marinkovic, Maja
author_sort Ing, Jordan
collection PubMed
description Disclosure: J. Ing: None. M. Marinkovic: None. Background: Evaluation for short stature routinely includes screening for hormone deficiencies, chromosomal abnormalities, gastroenterological diseases, and inflammatory processes. “Incorrect age” resulting in falsely short stature, is not often considered in the differential diagnosis. Clinical Case: A young girl who recently immigrated to the United States from Afghanistan was referred for endocrine evaluation for short stature. At the time of her initial visit, she was listed in the electronic medical record at 10 years and 0 months old. Her medical history was significant for bowel injuries sustained three years prior in a bombing incident that required surgery and from which she completely recovered. Available growth charts from the preceding 6 months showed height and weight consistently less than the 1(st) percentile for her age but normal height velocity. On the exam she was prepubertal. Her measured height was 117.8 cm (0.06(th) percentile, Z = -3.24) and her body mass index (BMI) was 14.7 kg/m(2) (12(th) percentile, Z = -1.18). The patient’s calculated mid-parental height was 155.5 cm (12.5(th) percentile, Z = -1.15). Laboratory work-up obtained by the pediatrician showed normal IGF-1, IGFBP-3, TSH, free and total thyroxine, tissue transglutaminase IgA, sedimentation rate, urinalysis, complete blood panel, complete metabolic panel, and a normal 20 cell count karyotype (46, XX). Her bone age was 5 years and 6 months and was interpreted as markedly delayed. Upon further history gathering using a Pashto interpreter, her father revealed there was an error in the processing of her immigration documents, resulting in being listed as three years older than her actual age. When corrected to that of a 7 year and 0 month old girl, her height improved to the 23(rd) percentile (Z = -0.73), and her BMI to the 31(st) percentile (Z = -0.5). Conclusion: This case demonstrates how children, through the immigration process, may have their age incorrectly documented and thereby are at risk for unnecessary and costly medical evaluation. It is possible that language barriers play a role in such errors. Therefore, it is important to verify the patient's true age, as parents may not think to provide this information voluntarily. Presentation: Thursday, June 15, 2023
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spelling pubmed-105557362023-10-07 THU175 Incorrect Age Causing Falsely Short Stature In An Afghan Immigrant Girl Ing, Jordan Marinkovic, Maja J Endocr Soc Pediatric Endocrinology Disclosure: J. Ing: None. M. Marinkovic: None. Background: Evaluation for short stature routinely includes screening for hormone deficiencies, chromosomal abnormalities, gastroenterological diseases, and inflammatory processes. “Incorrect age” resulting in falsely short stature, is not often considered in the differential diagnosis. Clinical Case: A young girl who recently immigrated to the United States from Afghanistan was referred for endocrine evaluation for short stature. At the time of her initial visit, she was listed in the electronic medical record at 10 years and 0 months old. Her medical history was significant for bowel injuries sustained three years prior in a bombing incident that required surgery and from which she completely recovered. Available growth charts from the preceding 6 months showed height and weight consistently less than the 1(st) percentile for her age but normal height velocity. On the exam she was prepubertal. Her measured height was 117.8 cm (0.06(th) percentile, Z = -3.24) and her body mass index (BMI) was 14.7 kg/m(2) (12(th) percentile, Z = -1.18). The patient’s calculated mid-parental height was 155.5 cm (12.5(th) percentile, Z = -1.15). Laboratory work-up obtained by the pediatrician showed normal IGF-1, IGFBP-3, TSH, free and total thyroxine, tissue transglutaminase IgA, sedimentation rate, urinalysis, complete blood panel, complete metabolic panel, and a normal 20 cell count karyotype (46, XX). Her bone age was 5 years and 6 months and was interpreted as markedly delayed. Upon further history gathering using a Pashto interpreter, her father revealed there was an error in the processing of her immigration documents, resulting in being listed as three years older than her actual age. When corrected to that of a 7 year and 0 month old girl, her height improved to the 23(rd) percentile (Z = -0.73), and her BMI to the 31(st) percentile (Z = -0.5). Conclusion: This case demonstrates how children, through the immigration process, may have their age incorrectly documented and thereby are at risk for unnecessary and costly medical evaluation. It is possible that language barriers play a role in such errors. Therefore, it is important to verify the patient's true age, as parents may not think to provide this information voluntarily. Presentation: Thursday, June 15, 2023 Oxford University Press 2023-10-05 /pmc/articles/PMC10555736/ http://dx.doi.org/10.1210/jendso/bvad114.1426 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of the Endocrine Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Pediatric Endocrinology
Ing, Jordan
Marinkovic, Maja
THU175 Incorrect Age Causing Falsely Short Stature In An Afghan Immigrant Girl
title THU175 Incorrect Age Causing Falsely Short Stature In An Afghan Immigrant Girl
title_full THU175 Incorrect Age Causing Falsely Short Stature In An Afghan Immigrant Girl
title_fullStr THU175 Incorrect Age Causing Falsely Short Stature In An Afghan Immigrant Girl
title_full_unstemmed THU175 Incorrect Age Causing Falsely Short Stature In An Afghan Immigrant Girl
title_short THU175 Incorrect Age Causing Falsely Short Stature In An Afghan Immigrant Girl
title_sort thu175 incorrect age causing falsely short stature in an afghan immigrant girl
topic Pediatric Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555736/
http://dx.doi.org/10.1210/jendso/bvad114.1426
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