Spatial single-cell mass spectrometry defines zonation of the hepatocyte proteome

Single-cell proteomics by mass spectrometry is emerging as a powerful and unbiased method for the characterization of biological heterogeneity. So far, it has been limited to cultured cells, whereas an expansion of the method to complex tissues would greatly enhance biological insights. Here we desc...

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Detalles Bibliográficos
Autores principales: Rosenberger, Florian A., Thielert, Marvin, Strauss, Maximilian T., Schweizer, Lisa, Ammar, Constantin, Mädler, Sophia C., Metousis, Andreas, Skowronek, Patricia, Wahle, Maria, Madden, Katherine, Gote-Schniering, Janine, Semenova, Anna, Schiller, Herbert B., Rodriguez, Edwin, Nordmann, Thierry M., Mund, Andreas, Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555842/
https://www.ncbi.nlm.nih.gov/pubmed/37783884
http://dx.doi.org/10.1038/s41592-023-02007-6

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