Kisspeptin treatment reverses high prolactin levels and improves gonadal function in hypothyroid male rats

We evaluated whether the administration of kisspeptin-10 (Kp10) is capable of restoring gonadal function in hypothyroid male rats. Hypothyroidism was induced with 6-propyl-2-thiouracil (PTU) for three months. In the last month, half of the hypothyroid animals were treated with Kp10. Hypothyroidism r...

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Detalles Bibliográficos
Autores principales: Santos, Luciano Cardoso, dos Anjos Cordeiro, Jeane Martinha, da Silva Santana, Larissa, Barbosa, Erikles Macêdo, Santos, Bianca Reis, Mendonça, Letícia Dias, Cunha, Maria Clara da Silva Galrão, Machado, William Morais, Santana, Larissa Rodrigues, Kersul, Maíra Guimarães, Henriques, Patrícia Costa, Lopes, Roberta Araújo, Snoeck, Paola Pereira das Neves, Szawka, Raphael Escorsim, Silva, Juneo Freitas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556046/
https://www.ncbi.nlm.nih.gov/pubmed/37798396
http://dx.doi.org/10.1038/s41598-023-44056-z

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