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Long term administration of loquat leaves and their major component, ursolic acid, attenuated endogenous amyloid-β burden and memory impairment

Loquat (Eriobotrya japonica) leaves contain many bioactive components such as ursolic acid (UA) and amygdalin. We investigated the effects of loquat leaf powder and methanol extract in human neuroglioma H4 cells stably expressing the Swedish-type APP695 (APP(NL)-H4 cells) and C57BL/6 J mice. Surpris...

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Detalles Bibliográficos
Autores principales:	Iwasa, Kensuke, Yagishita, Sosuke, Yagishita-Kyo, Nan, Yamagishi, Anzu, Yamamoto, Shinji, Yamashina, Kota, Haruta, Chikara, Asai, Masashi, Maruyama, Kei, Shimizu, Kuniyoshi, Yoshikawa, Keisuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556093/ https://www.ncbi.nlm.nih.gov/pubmed/37798424 http://dx.doi.org/10.1038/s41598-023-44098-3

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