Pan-tissue mitochondrial phenotyping reveals lower OXPHOS expression and function across cancer types

Targeting mitochondrial oxidative phosphorylation (OXPHOS) to treat cancer has been hampered due to serious side-effects potentially arising from the inability to discriminate between non-cancerous and cancerous mitochondria. Herein, comprehensive mitochondrial phenotyping was leveraged to define bo...

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Detalles Bibliográficos
Autores principales: Boykov, Ilya N., Montgomery, McLane M., Hagen, James T., Aruleba, Raphael T., McLaughlin, Kelsey L., Coalson, Hannah S., Nelson, Margaret A., Pereyra, Andrea S., Ellis, Jessica M., Zeczycki, Tonya N., Vohra, Nasreen A., Tan, Su-Fern, Cabot, Myles C., Fisher-Wellman, Kelsey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556099/
https://www.ncbi.nlm.nih.gov/pubmed/37798427
http://dx.doi.org/10.1038/s41598-023-43963-5

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