Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes

Understanding the human antibody response to emerging viral pathogens is key to epidemic preparedness. As the size of the B cell response to a pathogenic-virus-protective antigen is poorly defined, we perform deep paired heavy- and light-chain sequencing in Ebola virus glycoprotein (EBOV-GP)-specifi...

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Detalles Bibliográficos
Autores principales: Chen, Elaine C., Gilchuk, Pavlo, Zost, Seth J., Ilinykh, Philipp A., Binshtein, Elad, Huang, Kai, Myers, Luke, Bonissone, Stefano, Day, Samuel, Kona, Chandrahaas R., Trivette, Andrew, Reidy, Joseph X., Sutton, Rachel E., Gainza, Christopher, Diaz, Summer, Williams, Jazmean K., Selverian, Christopher N., Davidson, Edgar, Saphire, Erica Ollmann, Doranz, Benjamin J., Castellana, Natalie, Bukreyev, Alexander, Carnahan, Robert H., Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556194/
https://www.ncbi.nlm.nih.gov/pubmed/37029928
http://dx.doi.org/10.1016/j.celrep.2023.112370

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