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Urgent and emergent repair of complex aortic aneurysms using an off-the-shelf branched device

INTRODUCTION: Endovascular repair using off-the-shelf endografts is a viable solution in patients with ruptured or symptomatic complex aortic aneurysms. This analysis aimed to present the peri-operative and follow-up outcomes in urgent and emergent cases managed with the t-Branch multibranched thora...

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Autores principales: Nana, Petroula, Spanos, Konstantinos, Jakimowicz, Tomasz, Torrealba, Jose I., Jama, Katarzyna, Panuccio, Giuseppe, Rohlffs, Fiona, Kölbel, Tilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556233/
https://www.ncbi.nlm.nih.gov/pubmed/37808886
http://dx.doi.org/10.3389/fcvm.2023.1277459
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author Nana, Petroula
Spanos, Konstantinos
Jakimowicz, Tomasz
Torrealba, Jose I.
Jama, Katarzyna
Panuccio, Giuseppe
Rohlffs, Fiona
Kölbel, Tilo
author_facet Nana, Petroula
Spanos, Konstantinos
Jakimowicz, Tomasz
Torrealba, Jose I.
Jama, Katarzyna
Panuccio, Giuseppe
Rohlffs, Fiona
Kölbel, Tilo
author_sort Nana, Petroula
collection PubMed
description INTRODUCTION: Endovascular repair using off-the-shelf endografts is a viable solution in patients with ruptured or symptomatic complex aortic aneurysms. This analysis aimed to present the peri-operative and follow-up outcomes in urgent and emergent cases managed with the t-Branch multibranched thoracoabdominal endograft. METHODS: Prospectively collected data from all consecutive urgent and emergent cases managed in two aortic centers between January 1st, 2014, to November 30th, 2022, using the t-Branch device (Cook Medical Inc., Bjaeverskov, Denmark) were analyzed. Patients presenting with ruptured aortic complex aneurysms were characterized as emergent and patients with aneurysms >90 mm of diameter, or symptomatic aneurysms were characterized as urgent. Technical success, 30-day mortality, major adverse events (MAE) and spinal cord ischemia (SCI) rates were assessed. RESULTS: 225 patients (36.5% females, 72.5 ± 2.8 years) were included; 73.0% were urgent. The mean aneurysm diameter was 109 ± 3.9 mm and 44.4% were type I–III TAAAs. Females (p = .03), para-renal aneurysms (p = .02) and ASA score IV (p < .001) were more common in emergent cases. Technical success was 97.8%. Thirty-day mortality and MAE rates were 17.8% and 30.6%, respectively. SCI rate was 14.7%, (4.8% paraplegia rate) with 22.2% of patients receiving prophylactic cerebrospinal drainage. Thirty-day mortality (13.3% vs. 26.7%, p = .04) and MAE (26.0% vs. 43.0%, p = .02) were more common among emergent cases while technical success (97.6% vs. 98.3%, p = .9), and SCI (13.3% vs. 18.3%, p = .4) were similar. Survival at 12-months was 83.5% (SE 5.9%) for the urgent and 77.1% (SE 8.2%) for the emergent group (log rank, p = 0.96). CONCLUSION: T-Branch represents an effective and safe solution for the management of urgent and emergent cases with complex aortic aneurysms, with high technical success, promising early mortality and SCI rates.
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spelling pubmed-105562332023-10-07 Urgent and emergent repair of complex aortic aneurysms using an off-the-shelf branched device Nana, Petroula Spanos, Konstantinos Jakimowicz, Tomasz Torrealba, Jose I. Jama, Katarzyna Panuccio, Giuseppe Rohlffs, Fiona Kölbel, Tilo Front Cardiovasc Med Cardiovascular Medicine INTRODUCTION: Endovascular repair using off-the-shelf endografts is a viable solution in patients with ruptured or symptomatic complex aortic aneurysms. This analysis aimed to present the peri-operative and follow-up outcomes in urgent and emergent cases managed with the t-Branch multibranched thoracoabdominal endograft. METHODS: Prospectively collected data from all consecutive urgent and emergent cases managed in two aortic centers between January 1st, 2014, to November 30th, 2022, using the t-Branch device (Cook Medical Inc., Bjaeverskov, Denmark) were analyzed. Patients presenting with ruptured aortic complex aneurysms were characterized as emergent and patients with aneurysms >90 mm of diameter, or symptomatic aneurysms were characterized as urgent. Technical success, 30-day mortality, major adverse events (MAE) and spinal cord ischemia (SCI) rates were assessed. RESULTS: 225 patients (36.5% females, 72.5 ± 2.8 years) were included; 73.0% were urgent. The mean aneurysm diameter was 109 ± 3.9 mm and 44.4% were type I–III TAAAs. Females (p = .03), para-renal aneurysms (p = .02) and ASA score IV (p < .001) were more common in emergent cases. Technical success was 97.8%. Thirty-day mortality and MAE rates were 17.8% and 30.6%, respectively. SCI rate was 14.7%, (4.8% paraplegia rate) with 22.2% of patients receiving prophylactic cerebrospinal drainage. Thirty-day mortality (13.3% vs. 26.7%, p = .04) and MAE (26.0% vs. 43.0%, p = .02) were more common among emergent cases while technical success (97.6% vs. 98.3%, p = .9), and SCI (13.3% vs. 18.3%, p = .4) were similar. Survival at 12-months was 83.5% (SE 5.9%) for the urgent and 77.1% (SE 8.2%) for the emergent group (log rank, p = 0.96). CONCLUSION: T-Branch represents an effective and safe solution for the management of urgent and emergent cases with complex aortic aneurysms, with high technical success, promising early mortality and SCI rates. Frontiers Media S.A. 2023-09-22 /pmc/articles/PMC10556233/ /pubmed/37808886 http://dx.doi.org/10.3389/fcvm.2023.1277459 Text en © 2023 Nana, Spanos, Jakimowicz, Torrealba, Jama, Panuccio, Rohlffs and Kölbel. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Nana, Petroula
Spanos, Konstantinos
Jakimowicz, Tomasz
Torrealba, Jose I.
Jama, Katarzyna
Panuccio, Giuseppe
Rohlffs, Fiona
Kölbel, Tilo
Urgent and emergent repair of complex aortic aneurysms using an off-the-shelf branched device
title Urgent and emergent repair of complex aortic aneurysms using an off-the-shelf branched device
title_full Urgent and emergent repair of complex aortic aneurysms using an off-the-shelf branched device
title_fullStr Urgent and emergent repair of complex aortic aneurysms using an off-the-shelf branched device
title_full_unstemmed Urgent and emergent repair of complex aortic aneurysms using an off-the-shelf branched device
title_short Urgent and emergent repair of complex aortic aneurysms using an off-the-shelf branched device
title_sort urgent and emergent repair of complex aortic aneurysms using an off-the-shelf branched device
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556233/
https://www.ncbi.nlm.nih.gov/pubmed/37808886
http://dx.doi.org/10.3389/fcvm.2023.1277459
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