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Substantially Delayed Maturation of Growth Plate Chondrocytes in “Humanized” PTH1R Mice with the H223R Mutation of Jansen's Disease

Activating parathyroid hormone (PTH)/PTH‐related Peptide (PTHrP) receptor (PTH1R) mutations causes Jansen's metaphyseal chondrodysplasia (JMC), a rare disease characterized by growth plate abnormalities, short stature, and PTH‐independent hypercalcemia. Previously generated transgenic JMC mouse...

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Detalles Bibliográficos
Autores principales:	Reyes, Monica, Firat, Damla, Hanna, Patrick, Khan, Mohd, Bruce, Michael, Shvedova, Maria, Kobayashi, Tatsuya, Schipani, Ernestina, Gardella, Thomas J., Jüppner, Harald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556264/ https://www.ncbi.nlm.nih.gov/pubmed/37808400 http://dx.doi.org/10.1002/jbm4.10802

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