Accounting for intensity variation in image analysis of large‐scale multiplexed clinical trial datasets

Multiplex immunofluorescence (mIF) imaging can provide comprehensive quantitative and spatial information for multiple immune markers for tumour immunoprofiling. However, application at scale to clinical trial samples sourced from multiple institutions is challenging due to pre‐analytical heterogene...

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Detalles Bibliográficos
Autores principales: Frei, Anja L, McGuigan, Anthony, Sinha, Ritik RAK, Glaire, Mark A, Jabbar, Faiz, Gneo, Luciana, Tomasevic, Tijana, Harkin, Andrea, Iveson, Tim J, Saunders, Mark, Oein, Karin, Maka, Noori, Pezella, Francesco, Campo, Leticia, Hay, Jennifer, Edwards, Joanne, Sansom, Owen J, Kelly, Caroline, Tomlinson, Ian, Kildal, Wanja, Kerr, Rachel S, Kerr, David J, Danielsen, Håvard E, Domingo, Enric, Church, David N, Koelzer, Viktor H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556275/
https://www.ncbi.nlm.nih.gov/pubmed/37697694
http://dx.doi.org/10.1002/cjp2.342

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