Cargando…

Kalkitoxin attenuates calcification of vascular smooth muscle cells via RUNX-2 signaling pathways

BACKGROUND: Kalkitoxin (KT) is an active lipopeptide isolated from the cyanobacterium Lyngbya majuscula found in the bed of the coral reef. Although KT suppresses cell division and inflammation, KT’s mechanism of action in vascular smooth muscle cells (VSMCs) is unidentified. Therefore, our main aim...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shrestha, Saroj K, Kim, Se-Woong, Soh, Yunjo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Veterinary Science 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556282/ https://www.ncbi.nlm.nih.gov/pubmed/38031648 http://dx.doi.org/10.4142/jvs.23148

Ejemplares similares

Kalkitoxin: A Potent Suppressor of Distant Breast Cancer Metastasis
por: Shrestha, Saroj Kumar, et al.
Publicado: (2023)

Kalkitoxin Reduces Osteoclast Formation and Resorption and Protects against Inflammatory Bone Loss
por: Li, Liang, et al.
Publicado: (2021)

Cdon suppresses vascular smooth muscle calcification via repression of the Wnt/Runx2 Axis
por: Ahn, Byeong-Yun, et al.
Publicado: (2023)

Carnosine attenuates vascular smooth muscle cells calcification through mTOR signaling pathway
por: Huang, Yi, et al.
Publicado: (2020)

Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification
por: Skenteris, Nikolaos T., et al.
Publicado: (2022)

Vascular calcification is coupled with phenotypic conversion of vascular smooth muscle cells through Klf5-mediated transactivation of the Runx2 promoter
por: Zhang, Jing, et al.
Publicado: (2014)

Signaling pathways involved in vascular smooth muscle cell calcification during hyperphosphatemia
por: Voelkl, Jakob, et al.
Publicado: (2019)

Melatonin Attenuates β-Glycerophosphate-Induced Calcification of Vascular Smooth Muscle Cells via a Wnt1/β-Catenin Signaling Pathway
por: Chen, Wei Ren, et al.
Publicado: (2019)

Galectin-3 induces vascular smooth muscle cells calcification via AMPK/TXNIP pathway
por: Tian, Lei, et al.
Publicado: (2022)

Periostin Augments Vascular Smooth Muscle Cell Calcification via β-Catenin Signaling
por: Alesutan, Ioana, et al.
Publicado: (2022)

Vascular Calcification Mechanisms: Updates and Renewed Insight into Signaling Pathways Involved in High Phosphate-Mediated Vascular Smooth Muscle Cell Calcification
por: Abbasian, Nima
Publicado: (2021)

Roles of Vascular Smooth Muscle Cells in Atherosclerotic Calcification
por: Woo, Sang-Ho, et al.
Publicado: (2023)

Inflammation and Vascular Calcification Causing Effects of Oxidized HDL are Attenuated by Adiponectin in Human Vascular Smooth Muscle Cells
por: Harun, Noor Hanisa, et al.
Publicado: (2019)

Aster saponin A(2) inhibits osteoclastogenesis through mitogen-activated protein kinase-c-Fos-NFATc1 signaling pathway
por: Su, Xiang-Dong, et al.
Publicado: (2022)

Characterization of Circular RNAs in Vascular Smooth Muscle Cells with Vascular Calcification
por: Ryu, Juhee, et al.
Publicado: (2019)

Porphyromonas gingivalis‐derived outer membrane vesicles promote calcification of vascular smooth muscle cells through ERK1/2‐RUNX2
por: Yang, Wen Wei, et al.
Publicado: (2016)

Adropin Inhibits Vascular Smooth Muscle Cell Osteogenic Differentiation to Alleviate Vascular Calcification via the JAK2/STAT3 Signaling Pathway
por: Wang, Li, et al.
Publicado: (2022)

Indoxyl Sulfate-induced Vascular Calcification is mediated through Altered Notch Signaling Pathway in Vascular Smooth Muscle Cells
por: Yamaguchi, Kazutoshi, et al.
Publicado: (2020)

Kalkitoxin Inhibits Angiogenesis, Disrupts Cellular Hypoxic Signaling, and Blocks Mitochondrial Electron Transport in Tumor Cells
por: Morgan, J. Brian, et al.
Publicado: (2015)

Long noncoding RNAs in vascular smooth muscle cells regulate vascular calcification
por: Jeong, Geon, et al.
Publicado: (2019)

The Role of Sirtuins in Osteogenic Differentiation of Vascular Smooth Muscle Cells and Vascular Calcification
por: Wang, Shuangshuang, et al.
Publicado: (2022)

Phenotypic plasticity of vascular smooth muscle cells in vascular calcification: Role of mitochondria
por: Liu, Yan Zhong, et al.
Publicado: (2022)

Increased β-adrenergic stimulation augments vascular smooth muscle cell calcification via PKA/CREB signalling
por: Moser, Barbara, et al.
Publicado: (2021)

Critical Parameters of the In Vitro Method of Vascular Smooth Muscle Cell Calcification
por: Hortells, Luis, et al.
Publicado: (2015)

Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts
por: Patel, Jessal J., et al.
Publicado: (2019)

Vascular Smooth Muscle Cell Neutral Sphingomyelinase 2 in the Release of Exosomes and Vascular Calcification
por: Pavlic, Angelina, et al.
Publicado: (2022)

Suppression of SIRT1 in Diabetic Conditions Induces Osteogenic Differentiation of Human Vascular Smooth Muscle Cells via RUNX2 Signalling
por: Bartoli-Leonard, F., et al.
Publicado: (2019)

Sitagliptin attenuates high glucose-induced alterations in migration, proliferation, calcification and apoptosis of vascular smooth muscle cells through ERK1/2 signal pathway
por: Shi, Lili, et al.
Publicado: (2017)

Analysis of crucial genes, pathways and construction of the molecular regulatory networks in vascular smooth muscle cell calcification
por: Wei, Xiaomin, et al.
Publicado: (2021)

Nano-hydroxyapatite accelerates vascular calcification via lysosome impairment and autophagy dysfunction in smooth muscle cells
por: Liu, Qi, et al.
Publicado: (2021)

Long non-coding RNA MALAT1 sponges miR-30c to promote the calcification of human vascular smooth muscle cells by regulating Runx2
por: Gong, Ying, et al.
Publicado: (2023)

RTEF-1 Inhibits Vascular Smooth Muscle Cell Calcification through Regulating Wnt/β-Catenin Signaling Pathway
por: Cong, Jingjing, et al.
Publicado: (2021)

Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling
por: Willems, Brecht A., et al.
Publicado: (2018)

Uremic serum-induced calcification of human aortic smooth muscle cells is a regulated process involving Klotho and RUNX2
por: Patidar, Ashish, et al.
Publicado: (2019)

Hydrogen sulfide inhibits the calcification and osteoblastic differentiation of vascular smooth muscle cells
por: Zavaczki, Erzsébet, et al.
Publicado: (2011)

Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness
por: Durham, Andrew L, et al.
Publicado: (2018)

p53 Regulates Mitochondrial Dynamics in Vascular Smooth Muscle Cell Calcification
por: Phadwal, Kanchan, et al.
Publicado: (2023)

The Contribution of Extracellular Vesicles From Senescent Endothelial and Vascular Smooth Muscle Cells to Vascular Calcification
por: Mas-Bargues, Cristina, et al.
Publicado: (2022)

MicroRNA26 attenuates vascular smooth muscle maturation via endothelial BMP signalling
por: Watterston, Charlene, et al.
Publicado: (2019)

SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease
por: Li, Wenxin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ml33thsnpg2rvhjobm1qs746uf