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Manic episode following psilocybin use in a man with bipolar II disorder: a case report

There has been an increase in research on the topic of psychedelic substances and their effects as treatment options in neuropsychiatric conditions. Psilocybin is a psychedelic drug that has recently garnered increased interest as an effective treatment modality for treatment-resistant depression, d...

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Autores principales: Halim, Haniya J., Burk, Bradley G., Fargason, Rachel E., Birur, Badari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556490/
https://www.ncbi.nlm.nih.gov/pubmed/37810598
http://dx.doi.org/10.3389/fpsyt.2023.1221131
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author Halim, Haniya J.
Burk, Bradley G.
Fargason, Rachel E.
Birur, Badari
author_facet Halim, Haniya J.
Burk, Bradley G.
Fargason, Rachel E.
Birur, Badari
author_sort Halim, Haniya J.
collection PubMed
description There has been an increase in research on the topic of psychedelic substances and their effects as treatment options in neuropsychiatric conditions. Psilocybin is a psychedelic drug that has recently garnered increased interest as an effective treatment modality for treatment-resistant depression, depression associated with terminal conditions, certain substance use disorders, and obsessive-compulsive disorder. However, sparse data exist as to the effects that psilocybin might have on patients at risk for mania, in large part secondary to the exclusion of this patient population from studies due to the concern for inducing mania or worsening illness course. We describe a case of a 21-year-old male with a recent diagnosis of bipolar II disorder who developed a manic episode following the ingestion of psilocybin in the form of hallucinogenic mushrooms. Given the incidence of depression in those with bipolar disorder, impulsivity, and a tendency to abuse substances associated with the illness, further research is needed into the risks of psilocybin and other psychedelic use in those with bipolar disorder.
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spelling pubmed-105564902023-10-07 Manic episode following psilocybin use in a man with bipolar II disorder: a case report Halim, Haniya J. Burk, Bradley G. Fargason, Rachel E. Birur, Badari Front Psychiatry Psychiatry There has been an increase in research on the topic of psychedelic substances and their effects as treatment options in neuropsychiatric conditions. Psilocybin is a psychedelic drug that has recently garnered increased interest as an effective treatment modality for treatment-resistant depression, depression associated with terminal conditions, certain substance use disorders, and obsessive-compulsive disorder. However, sparse data exist as to the effects that psilocybin might have on patients at risk for mania, in large part secondary to the exclusion of this patient population from studies due to the concern for inducing mania or worsening illness course. We describe a case of a 21-year-old male with a recent diagnosis of bipolar II disorder who developed a manic episode following the ingestion of psilocybin in the form of hallucinogenic mushrooms. Given the incidence of depression in those with bipolar disorder, impulsivity, and a tendency to abuse substances associated with the illness, further research is needed into the risks of psilocybin and other psychedelic use in those with bipolar disorder. Frontiers Media S.A. 2023-09-22 /pmc/articles/PMC10556490/ /pubmed/37810598 http://dx.doi.org/10.3389/fpsyt.2023.1221131 Text en Copyright © 2023 Halim, Burk, Fargason and Birur. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Halim, Haniya J.
Burk, Bradley G.
Fargason, Rachel E.
Birur, Badari
Manic episode following psilocybin use in a man with bipolar II disorder: a case report
title Manic episode following psilocybin use in a man with bipolar II disorder: a case report
title_full Manic episode following psilocybin use in a man with bipolar II disorder: a case report
title_fullStr Manic episode following psilocybin use in a man with bipolar II disorder: a case report
title_full_unstemmed Manic episode following psilocybin use in a man with bipolar II disorder: a case report
title_short Manic episode following psilocybin use in a man with bipolar II disorder: a case report
title_sort manic episode following psilocybin use in a man with bipolar ii disorder: a case report
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556490/
https://www.ncbi.nlm.nih.gov/pubmed/37810598
http://dx.doi.org/10.3389/fpsyt.2023.1221131
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