A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells

Lung cancer is the leading cause of cancer deaths. Its high mortality is associated with high metastatic potential. Here, we show that the RAC1-selective guanine nucleotide exchange factor T cell invasion and metastasis-inducing protein 1 (TIAM1) promotes cell migration and invasion in the most comm...

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Detalles Bibliográficos
Autores principales: Ginn, Lucy, Maltas, Joe, Baker, Martin J., Chaturvedi, Anshuman, Wilson, Leah, Guilbert, Ryan, Amaral, Fabio M. R., Priest, Lynsey, Mole, Holly, Blackhall, Fiona, Diamantopoulou, Zoi, Somervaille, Tim C. P., Hurlstone, Adam, Malliri, Angeliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556593/
https://www.ncbi.nlm.nih.gov/pubmed/37748077
http://dx.doi.org/10.1073/pnas.2300489120

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