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Acute spinal cord infarction secondary to ankylosing spondylitis: a case report and literature review

INTRODUCTION: Spinal cord infarction secondary to ankylosing spondylitis is a rare but severe disorder. CASE PRESENTATION: Here we present a case of acute spinal cord infarction in a 54 years-old man with a medical history of ankylosing spondylitis, scoliosis, and hypotension. The patient complained...

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Autores principales: Li, Wenjuan, Guo, Jia, Wang, Lei, Zhang, Tinghua, Li, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556649/
https://www.ncbi.nlm.nih.gov/pubmed/37808493
http://dx.doi.org/10.3389/fneur.2023.1221810
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author Li, Wenjuan
Guo, Jia
Wang, Lei
Zhang, Tinghua
Li, Tian
author_facet Li, Wenjuan
Guo, Jia
Wang, Lei
Zhang, Tinghua
Li, Tian
author_sort Li, Wenjuan
collection PubMed
description INTRODUCTION: Spinal cord infarction secondary to ankylosing spondylitis is a rare but severe disorder. CASE PRESENTATION: Here we present a case of acute spinal cord infarction in a 54 years-old man with a medical history of ankylosing spondylitis, scoliosis, and hypotension. The patient complained of a sudden onset of lower limb weakness. A physical examination showed that he suffered from a dissociative sensory disorder, paralysis, and concomitant sphincter disturbances. After undergoing a whole-spine MRI, he was diagnosed with an acute ischemic injury from T2 to T5. As he did not treat his ankylosing spondylitis, it later caused a spinal deformity, making the lumbar puncture technically challenging. However, using Taylor’s approach, a CSF sample was successfully obtained. A CSF biochemical test ruled out myelitis, NMOSD, and MS. After receiving treatment with low-molecular-weight heparin, atorvastatin calcium, and methylprednisolone, his sphincter function gradually recovered, but his strength was only partially restored. CONCLUSION: Although this is a rare entity, it is necessary for physicians to consider it when evaluating patients with a sudden loss of sensation and strength in their lower limbs.
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spelling pubmed-105566492023-10-07 Acute spinal cord infarction secondary to ankylosing spondylitis: a case report and literature review Li, Wenjuan Guo, Jia Wang, Lei Zhang, Tinghua Li, Tian Front Neurol Neurology INTRODUCTION: Spinal cord infarction secondary to ankylosing spondylitis is a rare but severe disorder. CASE PRESENTATION: Here we present a case of acute spinal cord infarction in a 54 years-old man with a medical history of ankylosing spondylitis, scoliosis, and hypotension. The patient complained of a sudden onset of lower limb weakness. A physical examination showed that he suffered from a dissociative sensory disorder, paralysis, and concomitant sphincter disturbances. After undergoing a whole-spine MRI, he was diagnosed with an acute ischemic injury from T2 to T5. As he did not treat his ankylosing spondylitis, it later caused a spinal deformity, making the lumbar puncture technically challenging. However, using Taylor’s approach, a CSF sample was successfully obtained. A CSF biochemical test ruled out myelitis, NMOSD, and MS. After receiving treatment with low-molecular-weight heparin, atorvastatin calcium, and methylprednisolone, his sphincter function gradually recovered, but his strength was only partially restored. CONCLUSION: Although this is a rare entity, it is necessary for physicians to consider it when evaluating patients with a sudden loss of sensation and strength in their lower limbs. Frontiers Media S.A. 2023-09-22 /pmc/articles/PMC10556649/ /pubmed/37808493 http://dx.doi.org/10.3389/fneur.2023.1221810 Text en Copyright © 2023 Li, Guo, Wang, Zhang and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Li, Wenjuan
Guo, Jia
Wang, Lei
Zhang, Tinghua
Li, Tian
Acute spinal cord infarction secondary to ankylosing spondylitis: a case report and literature review
title Acute spinal cord infarction secondary to ankylosing spondylitis: a case report and literature review
title_full Acute spinal cord infarction secondary to ankylosing spondylitis: a case report and literature review
title_fullStr Acute spinal cord infarction secondary to ankylosing spondylitis: a case report and literature review
title_full_unstemmed Acute spinal cord infarction secondary to ankylosing spondylitis: a case report and literature review
title_short Acute spinal cord infarction secondary to ankylosing spondylitis: a case report and literature review
title_sort acute spinal cord infarction secondary to ankylosing spondylitis: a case report and literature review
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556649/
https://www.ncbi.nlm.nih.gov/pubmed/37808493
http://dx.doi.org/10.3389/fneur.2023.1221810
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