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Therapeutic potential of single-nucleotide polymorphism-mediated interleukin-6 receptor blockade in cancer treatment: A Mendelian randomization study

BACKGROUND: Interleukin-6 (IL-6) is a crucial member of the cytokine network and plays a pivotal role in the pathogenesis of various diseases, including cancer. IL-6 receptor (IL-6R) blockade is widely employed as a therapeutic strategy; however, its efficacy in anticancer therapy remains ambiguous....

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Detalles Bibliográficos
Autores principales:	Zhang, Shuwan, Zhang, Wenchuan, Sun, Hanxue, Xue, Rui, Lv, Qingjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556766/ https://www.ncbi.nlm.nih.gov/pubmed/37810867 http://dx.doi.org/10.1016/j.heliyon.2023.e20474

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