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Textbook outcome for the Norwood operation—an informative quality metric in congenital heart surgery
OBJECTIVES: To develop a more holistic measure of center performance than operative mortality, we created a composite “textbook outcome” for the Norwood operation using several postoperative end points. We hypothesized that achieving the textbook outcome would have a positive prognostic and financia...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556845/ https://www.ncbi.nlm.nih.gov/pubmed/37808016 http://dx.doi.org/10.1016/j.xjon.2023.05.003 |
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author | Prabhu, Neel K. Nellis, Joseph R. Moya-Mendez, Mary Hoover, Anna Medina, Cathlyn Meza, James M. Allareddy, Veerajalandhar Andersen, Nicholas D. Turek, Joseph W. |
author_facet | Prabhu, Neel K. Nellis, Joseph R. Moya-Mendez, Mary Hoover, Anna Medina, Cathlyn Meza, James M. Allareddy, Veerajalandhar Andersen, Nicholas D. Turek, Joseph W. |
author_sort | Prabhu, Neel K. |
collection | PubMed |
description | OBJECTIVES: To develop a more holistic measure of center performance than operative mortality, we created a composite “textbook outcome” for the Norwood operation using several postoperative end points. We hypothesized that achieving the textbook outcome would have a positive prognostic and financial impact. METHODS: This was a single-center retrospective study of primary Norwood operations from 2005 to 2021. Through interdisciplinary clinician consensus, textbook outcome was defined as freedom from operative mortality, open or catheter-based reintervention, 30-day readmission, extracorporeal membrane oxygenation, cardiac arrest, reintubation, length of stay >75%ile from Society of Thoracic Surgeons data report (66 days), and mechanical ventilation duration >75%ile (10 days). Multivariable logistic regression and Cox proportional hazards modeling were used to determine predictive factors for textbook outcome achievement and association of the outcome with long-term survival, respectively. RESULTS: Overall, 30% (58/196) of patients met the textbook outcome. Common reasons for failure to attain textbook outcome were prolonged ventilation (68/138, 49%) and reintubation (63/138, 46%). In multivariable analysis, greater weight (odds ratio [OR], 2.11; 95% confidence interval [CI], 1.17-3.95; P = .02) was associated with achieving the textbook outcome whereas preoperative shock (OR, 0.36; 95% CI, 0.13-0.87; P = .03) and longer bypass time (OR, 0.99; 95% CI, 0.98-1.00; P = .002) were negatively associated. Patients who met the outcome incurred fewer hospital costs ($152,430 [141,798-177,983] vs $269,070 [212,451-372,693], P < .001), and after adjusting for patient factors, achieving textbook outcome was independently associated with decreased risk of all-cause mortality (hazard ratio, 0.45; 95% CI, 0.22-0.89; P = .02). CONCLUSIONS: Outcomes continue to improve within congenital heart surgery, making operative mortality a less-sensitive metric. The Norwood textbook outcome may represent a balanced measure of a successful episode of care. |
format | Online Article Text |
id | pubmed-10556845 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-105568452023-10-07 Textbook outcome for the Norwood operation—an informative quality metric in congenital heart surgery Prabhu, Neel K. Nellis, Joseph R. Moya-Mendez, Mary Hoover, Anna Medina, Cathlyn Meza, James M. Allareddy, Veerajalandhar Andersen, Nicholas D. Turek, Joseph W. JTCVS Open Congenital: Norwood OBJECTIVES: To develop a more holistic measure of center performance than operative mortality, we created a composite “textbook outcome” for the Norwood operation using several postoperative end points. We hypothesized that achieving the textbook outcome would have a positive prognostic and financial impact. METHODS: This was a single-center retrospective study of primary Norwood operations from 2005 to 2021. Through interdisciplinary clinician consensus, textbook outcome was defined as freedom from operative mortality, open or catheter-based reintervention, 30-day readmission, extracorporeal membrane oxygenation, cardiac arrest, reintubation, length of stay >75%ile from Society of Thoracic Surgeons data report (66 days), and mechanical ventilation duration >75%ile (10 days). Multivariable logistic regression and Cox proportional hazards modeling were used to determine predictive factors for textbook outcome achievement and association of the outcome with long-term survival, respectively. RESULTS: Overall, 30% (58/196) of patients met the textbook outcome. Common reasons for failure to attain textbook outcome were prolonged ventilation (68/138, 49%) and reintubation (63/138, 46%). In multivariable analysis, greater weight (odds ratio [OR], 2.11; 95% confidence interval [CI], 1.17-3.95; P = .02) was associated with achieving the textbook outcome whereas preoperative shock (OR, 0.36; 95% CI, 0.13-0.87; P = .03) and longer bypass time (OR, 0.99; 95% CI, 0.98-1.00; P = .002) were negatively associated. Patients who met the outcome incurred fewer hospital costs ($152,430 [141,798-177,983] vs $269,070 [212,451-372,693], P < .001), and after adjusting for patient factors, achieving textbook outcome was independently associated with decreased risk of all-cause mortality (hazard ratio, 0.45; 95% CI, 0.22-0.89; P = .02). CONCLUSIONS: Outcomes continue to improve within congenital heart surgery, making operative mortality a less-sensitive metric. The Norwood textbook outcome may represent a balanced measure of a successful episode of care. Elsevier 2023-05-30 /pmc/articles/PMC10556845/ /pubmed/37808016 http://dx.doi.org/10.1016/j.xjon.2023.05.003 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Congenital: Norwood Prabhu, Neel K. Nellis, Joseph R. Moya-Mendez, Mary Hoover, Anna Medina, Cathlyn Meza, James M. Allareddy, Veerajalandhar Andersen, Nicholas D. Turek, Joseph W. Textbook outcome for the Norwood operation—an informative quality metric in congenital heart surgery |
title | Textbook outcome for the Norwood operation—an informative quality metric in congenital heart surgery |
title_full | Textbook outcome for the Norwood operation—an informative quality metric in congenital heart surgery |
title_fullStr | Textbook outcome for the Norwood operation—an informative quality metric in congenital heart surgery |
title_full_unstemmed | Textbook outcome for the Norwood operation—an informative quality metric in congenital heart surgery |
title_short | Textbook outcome for the Norwood operation—an informative quality metric in congenital heart surgery |
title_sort | textbook outcome for the norwood operation—an informative quality metric in congenital heart surgery |
topic | Congenital: Norwood |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556845/ https://www.ncbi.nlm.nih.gov/pubmed/37808016 http://dx.doi.org/10.1016/j.xjon.2023.05.003 |
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