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Mitochondrial heteroplasmic shifts reveal a positive selection of breast cancer

BACKGROUND: Breast cancer is, despite screening, not always detected early enough and is together with other tumor types known to shed genetic information in circulation. Unlike single-copy nuclear DNA, mitochondrial DNA (mtDNA) copies range from 100s to 10,000s per cell, thus providing a potentiall...

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Detalles Bibliográficos
Autores principales: Li, Yanni, Sundquist, Kristina, Vats, Sakshi, Hong, Mun-Gwan, Wang, Xiao, Chen, Yilun, Hedelius, Anna, Saal, Lao H., Sundquist, Jan, Memon, Ashfaque A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557196/
https://www.ncbi.nlm.nih.gov/pubmed/37798736
http://dx.doi.org/10.1186/s12967-023-04534-4