Cargando…

Mitochondrial heteroplasmic shifts reveal a positive selection of breast cancer

BACKGROUND: Breast cancer is, despite screening, not always detected early enough and is together with other tumor types known to shed genetic information in circulation. Unlike single-copy nuclear DNA, mitochondrial DNA (mtDNA) copies range from 100s to 10,000s per cell, thus providing a potentiall...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yanni, Sundquist, Kristina, Vats, Sakshi, Hong, Mun-Gwan, Wang, Xiao, Chen, Yilun, Hedelius, Anna, Saal, Lao H., Sundquist, Jan, Memon, Ashfaque A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557196/ https://www.ncbi.nlm.nih.gov/pubmed/37798736 http://dx.doi.org/10.1186/s12967-023-04534-4

Ejemplares similares

Characterization of the Mitochondrial Genetic Landscape in Abdominal Aortic Aneurysm
por: Vats, Sakshi, et al.
Publicado: (2023)

Diagnostic potential of circulating cell‐free nuclear and mitochondrial DNA for several cancer types and nonmalignant diseases: A study on suspected cancer patients
por: Sundquist, Kristina, et al.
Publicado: (2020)

Association of Mitochondrial DNA Copy Number and Telomere Length with Prevalent and Incident Cancer and Cancer Mortality in Women: A Prospective Swedish Population-Based Study
por: Li, Yanni, et al.
Publicado: (2021)

Association of mitochondrial DNA copy number with prevalent and incident type 2 diabetes in women: A population-based follow-up study
por: Memon, Ashfaque A., et al.
Publicado: (2021)

Quantification of mitochondrial DNA copy number in suspected cancer patients by a well optimized ddPCR method
por: Memon, Ashfaque A., et al.
Publicado: (2017)

Circulating microRNA-144-5p is associated with depressive disorders
por: Wang, Xiao, et al.
Publicado: (2015)

Leukocyte telomere length and depression, anxiety and stress and adjustment disorders in primary health care patients
por: Wang, Xiao, et al.
Publicado: (2017)

Association of circulating let-7b-5p with major depressive disorder: a nested case-control study
por: Roumans, Sanne, et al.
Publicado: (2021)

The association of zonulin-related proteins with prevalent and incident inflammatory bowel disease
por: Wang, Xiao, et al.
Publicado: (2022)

Mitochondrial related genome-wide Mendelian randomization identifies putatively causal genes for multiple cancer types
por: Li, Yanni, et al.
Publicado: (2023)

Baseline mitochondrial DNA copy number and heart failure incidence and its role in overall and heart failure mortality in middle-aged women
por: Sundquist, Kristina, et al.
Publicado: (2022)

Macrophage Migration Inhibitory Factor and microRNA-451a in Response to Mindfulness-based Therapy or Treatment as Usual in Patients with Depression, Anxiety, or Stress and Adjustment Disorders
por: Wang, Xiao, et al.
Publicado: (2018)

Mitochondria-DNA copy-number and incident venous thromboembolism among middle-aged women: a population-based cohort study
por: Nymberg, Peter, et al.
Publicado: (2021)

The association between cytokines and insulin sensitivity in Iraqi immigrants and native Swedes
por: Memon, Ashfaque A, et al.
Publicado: (2013)

Women’s health in the Lund area (WHILA) - Alcohol consumption and all-cause mortality among women – a 17 year follow-up study
por: Midlöv, Patrik, et al.
Publicado: (2016)

Risk prediction of recurrent venous thromboembolism: a multiple genetic risk model
por: Ahmad, Abrar, et al.
Publicado: (2018)

Association between TLR9 rs5743836 polymorphism and risk of recurrent venous thromboembolism
por: Ahmad, Abrar, et al.
Publicado: (2017)

Determination of 14 Circulating microRNAs in Swedes and Iraqis with and without Diabetes Mellitus Type 2
por: Wang, Xiao, et al.
Publicado: (2014)

Selective removal of deletion-bearing mitochondrial DNA in heteroplasmic Drosophila
por: Kandul, Nikolay P., et al.
Publicado: (2016)

Digested wheat gluten inhibits binding between leptin and its receptor
por: Jönsson, Tommy, et al.
Publicado: (2015)

Association of recurrent venous thromboembolism and circulating microRNAs
por: Wang, Xiao, et al.
Publicado: (2019)

Elucidating causal effects of type 2 diabetes on ischemic heart disease from observational data on middle-aged Swedish women: a triangular analytical approach
por: Sundquist, Kristina, et al.
Publicado: (2021)

Detection of Heteroplasmic Mitochondrial DNA in Single Mitochondria
por: Reiner, Joseph E., et al.
Publicado: (2010)

Heteroplasmic mitochondrial DNA variants in cardiovascular diseases
por: Calabrese, Claudia, et al.
Publicado: (2022)

Yoga’s effect on inflammatory biomarkers and metabolic risk factors in a high risk population – a controlled trial in primary care
por: Wolff, Moa, et al.
Publicado: (2015)

Heteroplasmic mitochondrial DNA mutations in normal and tumor cells
por: He, Yiping, et al.
Publicado: (2010)

Recent Advances in Detecting Mitochondrial DNA Heteroplasmic Variations
por: Duan, Mengqin, et al.
Publicado: (2018)

Heteroplasmic mitochondrial DNA mutations in frontotemporal lobar degeneration
por: Nie, Yu, et al.
Publicado: (2022)

Heteroplasmic mitochondrial genomes of a Raillietina tapeworm in wild Pangolin
por: Tuli, Merga Daba, et al.
Publicado: (2022)

Identifying actionable druggable targets for breast cancer: Mendelian randomization and population-based analyses
por: Zhang, Naiqi, et al.
Publicado: (2023)

Heteroplasmic Variants of Mitochondrial DNA in Atherosclerotic Lesions of Human Aortic Intima
por: Sobenin, Igor A., et al.
Publicado: (2019)

The Detection and Partial Localisation of Heteroplasmic Mutations in the Mitochondrial Genome of Patients with Diabetic Retinopathy
por: Malik, Afshan N., et al.
Publicado: (2019)

Use of Selective Serotonin Reuptake Inhibitors Is Associated with a Lower Risk of Colorectal Cancer among People with Family History
por: Zhang, Naiqi, et al.
Publicado: (2022)

Data on heteroplasmic mutations in mitochondrial genomes of loggerhead and hawksbill sea turtles: First approach
por: Delgado-Cano, David, et al.
Publicado: (2019)

Deleterious heteroplasmic mitochondrial mutations are associated with an increased risk of overall and cancer-specific mortality
por: Hong, Yun Soo, et al.
Publicado: (2023)

Halibut mitochondrial genomes contain extensive heteroplasmic tandem repeat arrays involved in DNA recombination
por: Mjelle, Kenneth A, et al.
Publicado: (2008)

A persistent mitochondrial deletion reduces fitness and sperm performance in heteroplasmic populations of C. elegans
por: Liau, Wei-Siang, et al.
Publicado: (2007)

Multiple Conserved Heteroplasmic Sites in tRNA Genes in the Mitochondrial Genomes of Terrestrial Isopods (Oniscidea)
por: Chandler, Christopher H., et al.
Publicado: (2015)

Autism and attention-deficit/hyperactivity disorder among individuals with a family history of alcohol use disorders
por: Sundquist, Jan, et al.
Publicado: (2014)

Association of tamoxifen with meningioma: a population-based study in Sweden
por: Ji, Jianguang, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_1hqgcv0td8pcokp8954fv373uj