Cargando…

A mutant methionyl-tRNA synthetase-based toolkit to assess induced-mesenchymal stromal cell secretome in mixed-culture disease models

Mostrar otras versiones (1)

BACKGROUND: Mesenchymal stromal cells (MSCs) have a dynamic secretome that plays a critical role in tissue repair and regeneration. However, studying the MSC secretome in mixed-culture disease models remains challenging. This study aimed to develop a mutant methionyl-tRNA synthetase-based toolkit (M...

Descripción completa

Detalles Bibliográficos
Autores principales:	Burgess, Jeremy D., Amerna, Danilyn, Norton, Emily S., Parsons, Tammee M., Perkerson, Ralph B., Faroqi, Ayman H., Wszolek, Zbigniew K., Guerrero Cazares, Hugo, Kanekiyo, Takahisa, Delenclos, Marion, McLean, Pamela J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557244/ https://www.ncbi.nlm.nih.gov/pubmed/37798772 http://dx.doi.org/10.1186/s13287-023-03515-0

Ejemplares similares

A Mutant Methionyl-tRNA Synthetase-Based toolkit to assess induced-Mesenchymal Stromal Cell secretome in mixed-culture disease models
por: Burgess, Jeremy D., et al.
Publicado: (2023)

Methionyl-tRNA Synthetase Regulates Lifespan in Drosophila
por: Suh, Yoon Seok, et al.
Publicado: (2020)

Structural basis for the dynamics of human methionyl-tRNA synthetase in multi-tRNA synthetase complexes
por: Kim, Dong Kyu, et al.
Publicado: (2021)

let-65 is cytoplasmic methionyl tRNA synthetase in C. elegans
por: Alriyami, Maha Z., et al.
Publicado: (2014)

Discovery of an Allosteric Binding Site in Kinetoplastid Methionyl-tRNA Synthetase
por: Torrie, Leah S., et al.
Publicado: (2020)

Characterization of the Secretome of a Specific Cell Expressing Mutant Methionyl-tRNA Synthetase in Co-Culture Using Click Chemistry
por: Shin, Sungho, et al.
Publicado: (2022)

Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani
por: Torrie, Leah S., et al.
Publicado: (2017)

Methionyl-tRNA synthetase novel mutation causes pulmonary alveolar proteinosis
por: Alzaid, Mohammed, et al.
Publicado: (2019)

Association of methionyl-tRNA synthetase with detergent-insoluble components of the rough endoplasmic reticulum
Publicado: (1983)

Nucleolar Localization of Human Methionyl–Trna Synthetase and Its Role in Ribosomal RNA Synthesis
por: Ko, Young-Gyu, et al.
Publicado: (2000)

High methionyl–tRNA synthetase expression predicts poor prognosis in patients with breast cancer
por: Jin, Qin, et al.
Publicado: (2020)

Promiscuous methionyl-tRNA synthetase mediates adaptive mistranslation to protect cells against oxidative stress
por: Lee, Jin Young, et al.
Publicado: (2014)

Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis
por: Ojo, Kayode K., et al.
Publicado: (2016)

Identifying potential natural inhibitors of Brucella melitensis Methionyl-tRNA synthetase through an in-silico approach
por: Rowaiye, Adekunle Babajide, et al.
Publicado: (2022)

Rare recessive loss-of-function methionyl-tRNA synthetase mutations presenting as a multi-organ phenotype
por: van Meel, Eline, et al.
Publicado: (2013)

Correction: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis
por: Ojo, Kayode K., et al.
Publicado: (2016)

Methionyl-tRNA synthetase overexpression is associated with poor clinical outcomes in non-small cell lung cancer
por: Kim, Eun Young, et al.
Publicado: (2017)

Prediction of Prognosis in Pancreatic Cancer According to Methionyl-tRNA Synthetase 1 Expression as Determined by Immunohistochemical Staining
por: Jang, Sung Ill, et al.
Publicado: (2023)

Honokiol decreases alpha-synuclein mRNA levels and reveals novel targets for modulating alpha-synuclein expression
por: Fagen, Sara J., et al.
Publicado: (2023)

Is Methionyl-tRNA Synthetase Applicable as a Diagnostic Marker for Lung Cancer in Bronchial Ultrasound-Guided Brushing Cells?
por: Lee, Kyungjong, et al.
Publicado: (2021)

Molecular basis for diaryldiamine selectivity and competition with tRNA in a type 2 methionyl-tRNA synthetase from a Gram-negative bacterium
por: Mercaldi, Gustavo Fernando, et al.
Publicado: (2021)

Mutations in the Mitochondrial Methionyl-tRNA Synthetase Cause a Neurodegenerative Phenotype in Flies and a Recessive Ataxia (ARSAL) in Humans
por: Bayat, Vafa, et al.
Publicado: (2012)

Methionyl-tRNA Synthetase is a Useful Diagnostic Marker for Lymph Node Metastasis in Non-Small Cell Lung Cancer
por: Lee, Jung Mo, et al.
Publicado: (2019)

Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness
por: Koh, Cho Yeow, et al.
Publicado: (2014)

Novel methionyl-tRNA synthetase gene variants/phenotypes in interstitial lung and liver disease: A case report and review of literature
por: Abuduxikuer, Kuerbanjiang, et al.
Publicado: (2018)

5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors
por: Zhang, Zhongsheng, et al.
Publicado: (2016)

Structural characterization of free-state and product-state Mycobacterium tuberculosis methionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism
por: Wang, Wei, et al.
Publicado: (2018)

Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase
por: Yi, Jia, et al.
Publicado: (2022)

Novel Hybrid Virtual Screening Protocol Based on Molecular Docking and Structure-Based Pharmacophore for Discovery of Methionyl-tRNA Synthetase Inhibitors as Antibacterial Agents
por: Liu, Chi, et al.
Publicado: (2013)

Mitochondrial Methionyl-tRNA Formyltransferase Deficiency Alleviates Metaflammation by Modulating Mitochondrial Activity in Mice
por: Sun, Xiaoxiao, et al.
Publicado: (2023)

Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase
por: Milne, Rachel, et al.
Publicado: (2022)

Methionyl-tRNA formyltransferase utilizes 10-formyldihydrofolate as an alternative substrate and impacts antifolate drug action
por: Sah, Shivjee, et al.
Publicado: (2023)

Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway
por: Park, Jae-Hyeon, et al.
Publicado: (2020)

Bacterial Aspartyl-tRNA Synthetase Has Glutamyl-tRNA Synthetase Activity
por: Rathnayake, Udumbara M., et al.
Publicado: (2019)

Aminoacyl-tRNA synthetases of the multi-tRNA synthetase complex and their role in tumorigenesis
por: Khan, Krishnendu, et al.
Publicado: (2022)

Aminoacyl-tRNA synthetases
por: Rubio Gomez, Miguel Angel, et al.
Publicado: (2020)

Roles of yeast eIF2α and eIF2β subunits in the binding of the initiator methionyl-tRNA
por: Naveau, Marie, et al.
Publicado: (2013)

Expanding a tyrosyl-tRNA synthetase assay to other aminoacyl-tRNA synthetases
por: Richardson, Charles J., et al.
Publicado: (2015)

In Vivo Detection of Extracellular Adenosine Triphosphate in a Mouse Model of Traumatic Brain Injury
por: Faroqi, Ayman H., et al.
Publicado: (2021)

Aminoacyl-tRNA Synthetases: On Anti-Synthetase Syndrome and Beyond
por: Galindo-Feria, Angeles S., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ov6kdmpjsdcrdup0ic6knge1aa