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ERK mediates interferon gamma-induced melanoma cell death

BACKGROUND: Interferon-gamma (IFNγ) exerts potent growth inhibitory effects on a wide range of cancer cells through unknown signaling pathways. We pursued complementary screening approaches to characterize the growth inhibition pathway. METHODS: We performed chemical genomics and whole genome target...

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Detalles Bibliográficos
Autores principales: Champhekar, Ameya, Heymans, Rachel, Saco, Justin, Turon Font, Guillem, Gonzalez, Cynthia, Gao, Anne, Pham, John, Lee, June, Maryoung, Ryan, Medina, Egmidio, Campbell, Katie M., Karin, Daniel, Austin, David, Damioseaux, Robert, Ribas, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557262/
https://www.ncbi.nlm.nih.gov/pubmed/37803324
http://dx.doi.org/10.1186/s12943-023-01868-x

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