Cargando…

A transgenic mice model of retinopathy of cblG-type inherited disorder of one-carbon metabolism highlights epigenome-wide alterations related to cone photoreceptor cells development and retinal metabolism

BACKGROUND: MTR gene encodes the cytoplasmic enzyme methionine synthase, which plays a pivotal role in the methionine cycle of one-carbon metabolism. This cycle holds a significant importance in generating S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH), the respective universal methyl d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matmat, Karim, Conart, Jean-Baptiste, Graindorge, Paul-Henri, El Kouche, Sandra, Hassan, Ziad, Siblini, Youssef, Umoret, Rémy, Safar, Ramia, Baspinar, Okan, Robert, Aurélie, Alberto, Jean-Marc, Oussalah, Abderrahim, Coelho, David, Guéant, Jean-Louis, Guéant-Rodriguez, Rosa-Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557304/ https://www.ncbi.nlm.nih.gov/pubmed/37798757 http://dx.doi.org/10.1186/s13148-023-01567-w

Ejemplares similares

Stemness of Normal and Cancer Cells: The Influence of Methionine Needs and SIRT1/PGC-1α/PPAR-α Players
por: Siblini, Youssef, et al.
Publicado: (2022)

Guidelines for diagnosis and management of the cobalamin-related remethylation disorders cblC, cblD, cblE, cblF, cblG, cblJ and MTHFR deficiency
por: Huemer, Martina, et al.
Publicado: (2016)

Ionizing radiations induce shared epigenomic signatures unraveling adaptive mechanisms of cancerous cell lines with or without methionine dependency
por: Siblini, Youssef, et al.
Publicado: (2021)

Epimutations in both the TESK2 and MMACHC promoters in the Epi-cblC inherited disorder of intracellular metabolism of vitamin B(12)
por: Oussalah, Abderrahim, et al.
Publicado: (2022)

Information-seeking Behavior During Residency Is Associated With Quality of Theoretical Learning, Academic Career Achievements, and Evidence-based Medical Practice: A Strobe-Compliant Article
por: Oussalah, Abderrahim, et al.
Publicado: (2015)

Cognitive Impairment Is Associated with AMPAR Glutamatergic Dysfunction in a Mouse Model of Neuronal Methionine Synthase Deficiency
por: Hassan, Ziad, et al.
Publicado: (2023)

Predictors of the utility of clinical exome sequencing as a first-tier genetic test in patients with Mendelian phenotypes: results from a referral center study on 603 consecutive cases
por: Alix, Tom, et al.
Publicado: (2023)

Sirt1-PPARS Cross-Talk in Complex Metabolic Diseases and Inherited Disorders of the One Carbon Metabolism
por: Kosgei, Viola J., et al.
Publicado: (2020)

Clinical, phenotypic and genetic landscape of case reports with genetically proven inherited disorders of vitamin B(12) metabolism: A meta-analysis
por: Wiedemann, Arnaud, et al.
Publicado: (2022)

Usefulness of procalcitonin at admission as a risk-stratifying biomarker for 50-day in-hospital mortality among patients with community-acquired bloodstream infection: an observational cohort study
por: Oussalah, Abderrahim, et al.
Publicado: (2023)

PRDX1 gene-related epi-cblC disease is a common type of inborn error of cobalamin metabolism with mono- or bi-allelic MMACHC epimutations
por: Cavicchi, Catia, et al.
Publicado: (2021)

Exome-Wide Association Study Identifies New Low-Frequency and Rare UGT1A1 Coding Variants and UGT1A6 Coding Variants Influencing Serum Bilirubin in Elderly Subjects: A Strobe Compliant Article
por: Oussalah, Abderrahim, et al.
Publicado: (2015)

Predictors of High Motivation Score for Performing Research Initiation Fellowship, Master 1, Research Master 2, and PhD Curricula During Medical Studies: A Strobe-Compliant Article
por: Feigerlova, Eva, et al.
Publicado: (2016)

Integrative genomics analysis of nasal intestinal-type adenocarcinomas demonstrates the major role of CACNA1C and paves the way for a simple diagnostic tool in male woodworkers
por: Gallet, Patrice, et al.
Publicado: (2021)

Diagnostic Accuracy of Procalcitonin for Predicting Blood Culture Results in Patients With Suspected Bloodstream Infection: An Observational Study of 35,343 Consecutive Patients (A STROBE-Compliant Article)
por: Oussalah, Abderrahim, et al.
Publicado: (2015)

Brain Susceptibility to Methyl Donor Deficiency: From Fetal Programming to Aging Outcome in Rats
por: Hassan, Ziad, et al.
Publicado: (2019)

MicroRNAs miR-16 and miR-519 control meningioma cell proliferation via overlapping transcriptomic programs shared with the RNA-binding protein HuR
por: Hergalant, Sébastien, et al.
Publicado: (2023)

A PRDX1 mutant allele causes a MMACHC secondary epimutation in cblC patients
por: Guéant, Jean-Louis, et al.
Publicado: (2018)

Global Burden Related to Nitrous Oxide Exposure in Medical and Recreational Settings: A Systematic Review and Individual Patient Data Meta-Analysis
por: Oussalah, Abderrahim, et al.
Publicado: (2019)

The Stimulation of Neurogenesis Improves the Cognitive Status of Aging Rats Subjected to Gestational and Perinatal Deficiency of B9–12 Vitamins
por: Pourié, Grégory, et al.
Publicado: (2020)

Publisher Correction: A PRDX1 mutant allele causes a MMACHC secondary epimutation in cblC patients
por: Guéant, Jean-Louis, et al.
Publicado: (2018)

Developmental Impairments in a Rat Model of Methyl Donor Deficiency: Effects of a Late Maternal Supplementation with Folic Acid
por: Geoffroy, Andréa, et al.
Publicado: (2019)

Foetal programming by methyl donor deficiency produces steato-hepatitis in rats exposed to high fat diet
por: Bison, Anaïs, et al.
Publicado: (2016)

Hypozincemia in the early stage of COVID-19 is associated with an increased risk of severe COVID-19
por: Fromonot, Julien, et al.
Publicado: (2022)

Methionine synthase A2756G polymorphism may predict ulcerative colitis and methylenetetrahydrofolate reductase C677T pancolitis, in Central China
por: Chen, Min, et al.
Publicado: (2008)

Coronavirus disease 2019: acute Fanconi syndrome precedes acute kidney injury
por: Kormann, Raphaël, et al.
Publicado: (2020)

Genetic associations in beta-lactam allergy
por: Gueant, Jean-Louis, et al.
Publicado: (2014)

Plasma mSEPT9: A Novel Circulating Cell-free DNA-Based Epigenetic Biomarker to Diagnose Hepatocellular Carcinoma
por: Oussalah, Abderrahim, et al.
Publicado: (2018)

Early incidence of occupational asthma among young bakers, pastry-makers and hairdressers: design of a retrospective cohort study
por: Rémen, Thomas, et al.
Publicado: (2010)

Methyl Donor Deficiency during Gestation and Lactation in the Rat Affects the Expression of Neuropeptides and Related Receptors in the Hypothalamus
por: Saber Cherif, Lynda, et al.
Publicado: (2019)

Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR
por: Battaglia-Hsu, Shyue-Fang, et al.
Publicado: (2018)

Folate and Cobalamin Deficiencies during Pregnancy Disrupt the Glucocorticoid Response in Hypothalamus through N-Homocysteinilation of the Glucocorticoid Receptor
por: Michel, Arnaud, et al.
Publicado: (2023)

The spectrum of biochemical alterations associated with organ dysfunction and inflammatory status and their association with disease outcomes in severe COVID-19: A longitudinal cohort and time-series design study
por: Oussalah, Abderrahim, et al.
Publicado: (2020)

Vitamin B12-Impaired Metabolism Produces Apoptosis and Parkinson Phenotype in Rats Expressing the Transcobalamin-Oleosin Chimera in Substantia Nigra
por: Orozco-Barrios, Carlos Enrique, et al.
Publicado: (2009)

The Fate of Transplanted Olfactory Progenitors Is Conditioned by the Cell Phenotypes of the Receiver Brain Tissue in Cocultures
por: Grégory, Pourié, et al.
Publicado: (2020)

Rôle prédictif des marqueurs de l’activation des neutrophiles dans les complications respiratoires résiduelles des pneumonies à SARS-CoV-2
por: Abel, T., et al.
Publicado: (2023)

Population and evolutionary genetics of the PAH locus to uncover overdominance and adaptive mechanisms in phenylketonuria: Results from a multiethnic study
por: Oussalah, Abderrahim, et al.
Publicado: (2020)

Cancer metabolism of cone photoreceptors
por: Léveillard, Thierry
Publicado: (2015)

Late Maternal Folate Supplementation Rescues from Methyl Donor Deficiency-Associated Brain Defects by Restoring Let-7 and miR-34 Pathways
por: Geoffroy, Andréa, et al.
Publicado: (2016)

BRIP1 coding variants are associated with a high risk of hepatocellular carcinoma occurrence in patients with HCV- or HBV-related liver disease
por: Oussalah, Abderrahim, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ug5ecn3bqib3hamf9f8rdmt7u5