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Determinants of astrocytic pathology in stem cell models of primary tauopathies

Astrocytic tau aggregates are seen in several primary and secondary tauopathies, including progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), and chronic traumatic encephalopathy (CTE). In all of these diseases, astrocytic tau consists mostly of the longer (4R) tau isoform, even...

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Detalles Bibliográficos
Autores principales: Fiock, Kimberly L., Hook, Jordan N., Hefti, Marco M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557325/
https://www.ncbi.nlm.nih.gov/pubmed/37803326
http://dx.doi.org/10.1186/s40478-023-01655-1