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Acute myeloid leukemia: from NGS, through scRNA-seq, to CAR-T. dissect cancer heterogeneity and tailor the treatment

Acute myeloid leukemia (AML) is a malignant blood cancer with marked cellular heterogeneity due to altered maturation and differentiation of myeloid blasts, the possible causes of which are transcriptional or epigenetic alterations, impaired apoptosis, and excessive cell proliferation. This neoplasm...

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Detalles Bibliográficos
Autores principales: Peroni, Edoardo, Randi, Maria Luigia, Rosato, Antonio, Cagnin, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557350/
https://www.ncbi.nlm.nih.gov/pubmed/37803464
http://dx.doi.org/10.1186/s13046-023-02841-8

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