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Phytochemical screening and anti-obesity, anti- diabetic and anti-oxidant properties of Scoparia dulcis leaf decoction (crude)

Due to their rising prevalence, diabetes and obesity were both classified as epidemics by the World Health Organization.The natural leaf essence of Scoparia dulcis (S. dulcis), is used as herbal remedy for diabetes and obesity worldwide. However, the objective of the current research was to examine...

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Detalles Bibliográficos
Autores principales: Mary, Arulandhu Clara, Ireen, Christopher, Vijayalakshmi, Periyasamy, Indhu, Sabapathy, Divyabharathi, Sekar, Felix, Kulandaisamy Suregka, Daisyrani, Viyagulasamy, Rajalakshmi, Manikkam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557454/
https://www.ncbi.nlm.nih.gov/pubmed/37808375
http://dx.doi.org/10.6026/97320630019238
Descripción
Sumario:Due to their rising prevalence, diabetes and obesity were both classified as epidemics by the World Health Organization.The natural leaf essence of Scoparia dulcis (S. dulcis), is used as herbal remedy for diabetes and obesity worldwide. However, the objective of the current research was to examine the effects of consuming commercially available S. dulcis porridge on both diabetes and obesity. The S. dulcis plants were collected and the essence was prepared in a traditional way. Phytochemical screening was carried out to identify the secondary metabolites present in the essence. The GC-MS analysis was carried out to identify the bioactive compounds present in the extracts. In order to understand the molecular interaction of identified compounds with selected target proteins from anti-diabetic, anti-oxidant, anti-obesity molecular docking studies was carried out. Results of this docking studies confirmed that identified compounds showed the strong interaction with all the selected target protein. Further experimental analysis is needed to confirm this activity.