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Phytochemical screening and anti-obesity, anti- diabetic and anti-oxidant properties of Scoparia dulcis leaf decoction (crude)

Due to their rising prevalence, diabetes and obesity were both classified as epidemics by the World Health Organization.The natural leaf essence of Scoparia dulcis (S. dulcis), is used as herbal remedy for diabetes and obesity worldwide. However, the objective of the current research was to examine...

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Autores principales: Mary, Arulandhu Clara, Ireen, Christopher, Vijayalakshmi, Periyasamy, Indhu, Sabapathy, Divyabharathi, Sekar, Felix, Kulandaisamy Suregka, Daisyrani, Viyagulasamy, Rajalakshmi, Manikkam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557454/
https://www.ncbi.nlm.nih.gov/pubmed/37808375
http://dx.doi.org/10.6026/97320630019238
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author Mary, Arulandhu Clara
Ireen, Christopher
Vijayalakshmi, Periyasamy
Indhu, Sabapathy
Divyabharathi, Sekar
Felix, Kulandaisamy Suregka
Daisyrani, Viyagulasamy
Rajalakshmi, Manikkam
author_facet Mary, Arulandhu Clara
Ireen, Christopher
Vijayalakshmi, Periyasamy
Indhu, Sabapathy
Divyabharathi, Sekar
Felix, Kulandaisamy Suregka
Daisyrani, Viyagulasamy
Rajalakshmi, Manikkam
author_sort Mary, Arulandhu Clara
collection PubMed
description Due to their rising prevalence, diabetes and obesity were both classified as epidemics by the World Health Organization.The natural leaf essence of Scoparia dulcis (S. dulcis), is used as herbal remedy for diabetes and obesity worldwide. However, the objective of the current research was to examine the effects of consuming commercially available S. dulcis porridge on both diabetes and obesity. The S. dulcis plants were collected and the essence was prepared in a traditional way. Phytochemical screening was carried out to identify the secondary metabolites present in the essence. The GC-MS analysis was carried out to identify the bioactive compounds present in the extracts. In order to understand the molecular interaction of identified compounds with selected target proteins from anti-diabetic, anti-oxidant, anti-obesity molecular docking studies was carried out. Results of this docking studies confirmed that identified compounds showed the strong interaction with all the selected target protein. Further experimental analysis is needed to confirm this activity.
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spelling pubmed-105574542023-10-07 Phytochemical screening and anti-obesity, anti- diabetic and anti-oxidant properties of Scoparia dulcis leaf decoction (crude) Mary, Arulandhu Clara Ireen, Christopher Vijayalakshmi, Periyasamy Indhu, Sabapathy Divyabharathi, Sekar Felix, Kulandaisamy Suregka Daisyrani, Viyagulasamy Rajalakshmi, Manikkam Bioinformation Research Article Due to their rising prevalence, diabetes and obesity were both classified as epidemics by the World Health Organization.The natural leaf essence of Scoparia dulcis (S. dulcis), is used as herbal remedy for diabetes and obesity worldwide. However, the objective of the current research was to examine the effects of consuming commercially available S. dulcis porridge on both diabetes and obesity. The S. dulcis plants were collected and the essence was prepared in a traditional way. Phytochemical screening was carried out to identify the secondary metabolites present in the essence. The GC-MS analysis was carried out to identify the bioactive compounds present in the extracts. In order to understand the molecular interaction of identified compounds with selected target proteins from anti-diabetic, anti-oxidant, anti-obesity molecular docking studies was carried out. Results of this docking studies confirmed that identified compounds showed the strong interaction with all the selected target protein. Further experimental analysis is needed to confirm this activity. Biomedical Informatics 2023-03-31 /pmc/articles/PMC10557454/ /pubmed/37808375 http://dx.doi.org/10.6026/97320630019238 Text en © 2023 Biomedical Informatics https://creativecommons.org/licenses/by/3.0/This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Mary, Arulandhu Clara
Ireen, Christopher
Vijayalakshmi, Periyasamy
Indhu, Sabapathy
Divyabharathi, Sekar
Felix, Kulandaisamy Suregka
Daisyrani, Viyagulasamy
Rajalakshmi, Manikkam
Phytochemical screening and anti-obesity, anti- diabetic and anti-oxidant properties of Scoparia dulcis leaf decoction (crude)
title Phytochemical screening and anti-obesity, anti- diabetic and anti-oxidant properties of Scoparia dulcis leaf decoction (crude)
title_full Phytochemical screening and anti-obesity, anti- diabetic and anti-oxidant properties of Scoparia dulcis leaf decoction (crude)
title_fullStr Phytochemical screening and anti-obesity, anti- diabetic and anti-oxidant properties of Scoparia dulcis leaf decoction (crude)
title_full_unstemmed Phytochemical screening and anti-obesity, anti- diabetic and anti-oxidant properties of Scoparia dulcis leaf decoction (crude)
title_short Phytochemical screening and anti-obesity, anti- diabetic and anti-oxidant properties of Scoparia dulcis leaf decoction (crude)
title_sort phytochemical screening and anti-obesity, anti- diabetic and anti-oxidant properties of scoparia dulcis leaf decoction (crude)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557454/
https://www.ncbi.nlm.nih.gov/pubmed/37808375
http://dx.doi.org/10.6026/97320630019238
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