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Diabetes mellitus drug discovery: insights into targeting feline and human amylin with small molecules
BACKGROUND: Type 2 diabetes (T2D) is a health concern for both humans and cats, with cases rising over the past decade. Around 70% of patients from either species exhibit pancreatic aggregates of islet amyloid polypeptide (IAPP), a protein that proves toxic upon misfolding. These misfolded protein a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557562/ https://www.ncbi.nlm.nih.gov/pubmed/37729105 http://dx.doi.org/10.1080/01652176.2023.2260442 |