TRIP13 localizes to synapsed chromosomes and functions as a dosage-sensitive regulator of meiosis

Meiotic progression requires coordinated assembly and disassembly of protein complexes involved in chromosome synapsis and meiotic recombination. The AAA+ ATPase TRIP13 and its orthologue Pch2 are instrumental in remodeling HORMA domain proteins. Meiosis-specific HORMAD proteins are associated with...

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Detalles Bibliográficos
Autores principales: Chotiner, Jessica Y., Leu, N. Adrian, Yang, Fang, Cossu, Isabella G., Guan, Yongjuan, Lin, Huijuan, Wang, P. Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557606/
https://www.ncbi.nlm.nih.gov/pubmed/37808842
http://dx.doi.org/10.1101/2023.09.25.559355

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