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Tenofovir Activation is Diminished in the Brain and Liver of Creatine Kinase Brain-Type Knockout Mice

Tenofovir (TFV) is a nucleotide reverse transcriptase inhibitor prescribed for the treatment and prevention of human immunodeficiency virus infection, and the treatment of chronic hepatitis B virus infection. Here, we demonstrate that creatine kinase brain-type (CKB) can form tenofovir-diphosphate (...

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Detalles Bibliográficos
Autores principales:	Eberhard, Colten D., Mosher, Eric P., Bumpus, Namandjé N., Orsburn, Benjamin C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557616/ https://www.ncbi.nlm.nih.gov/pubmed/37808667 http://dx.doi.org/10.1101/2023.09.25.559370

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