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Replication-dead gammaherpesvirus vaccine protects against acute replication, reactivation from latency, and lethal challenge in mice
Gammaherpesviruses (GHVs) are oncogenic viruses that establish lifelong infections and are significant causes of human morbidity and mortality. While several vaccine strategies to limit GHV infection and disease are in development, there are no FDA-approved vaccines for human GHVs. As a new approach...
Autores principales: | Bland, Wesley A., Owens, Shana, McEvoy, Kyle, Hogan, Chad H., Boccuzzi, Luciarita, Kirillov, Varvara, Khairallah, Camille, Sheridan, Brian S., Forrest, J. Craig, Krug, Laurie T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557649/ https://www.ncbi.nlm.nih.gov/pubmed/37808844 http://dx.doi.org/10.1101/2023.09.26.559621 |
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