Cargando…

Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse model

Abnormal cellular and circuit excitability is believed to drive many core phenotypes in fragile X syndrome (FXS). The dentate gyrus is a brain area performing critical computations essential for learning and memory. However, little is known about dentate circuit defects and their mechanisms in FXS....

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Pan-Yue, Kumar, Ajeet, Cavalli, Valeria, Klyachko, Vitaly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557679/
https://www.ncbi.nlm.nih.gov/pubmed/37808793
http://dx.doi.org/10.1101/2023.09.27.559792