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Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse model
Abnormal cellular and circuit excitability is believed to drive many core phenotypes in fragile X syndrome (FXS). The dentate gyrus is a brain area performing critical computations essential for learning and memory. However, little is known about dentate circuit defects and their mechanisms in FXS....
Autores principales: | Deng, Pan-Yue, Kumar, Ajeet, Cavalli, Valeria, Klyachko, Vitaly A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557679/ https://www.ncbi.nlm.nih.gov/pubmed/37808793 http://dx.doi.org/10.1101/2023.09.27.559792 |
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