Disruption of Epithelium Integrity by Inflammation-Associated Fibroblasts through Prostaglandin Signaling: IAFs disrupt colon epithelium via PGE2-EP4

Inflammation-associated fibroblasts (IAFs) are associated with the progression and drug resistance of chronic inflammatory diseases such as inflammatory bowel disease (IBD), but their direct impact on epithelial function and architecture is unknown. In this study, we developed an in vitro model wher...

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Detalles Bibliográficos
Autores principales: Dong, Yi, Johnson, Blake A., Ruan, Linhao, Zeineldin, Maged, Liu, Albert Z., Raychaudhuri, Sumana, Chiu, Ian, Zhu, Jin, Smith, Barbara, Zhao, Nan, Searson, Peter, Watanabe, Shigeki, Donowitz, Mark, Larman, Tatianna C., Li, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557697/
https://www.ncbi.nlm.nih.gov/pubmed/37808771
http://dx.doi.org/10.1101/2023.09.28.560060

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