Molecular and network disruptions in neurodevelopment uncovered by single cell transcriptomics analysis of CHD8 heterozygous cerebral organoids

About 100 genes have been associated with significantly increased risks of autism spectrum disorders (ASD) with an estimate of ~1000 genes that may be involved. The new challenge now is to investigate the molecular and cellular functions of these genes during neural and brain development, and then e...

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Detalles Bibliográficos
Autores principales: Astorkia, Maider, Liu, Yang, Pedrosa, Erika M., Lachman, Herbert M., Zheng, Deyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557718/
https://www.ncbi.nlm.nih.gov/pubmed/37808768
http://dx.doi.org/10.1101/2023.09.27.559752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557718/
https://www.ncbi.nlm.nih.gov/pubmed/37808768
http://dx.doi.org/10.1101/2023.09.27.559752

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