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Ethanol stress induces transient restructuring of the yeast genome yet stable formation of Hsf1 transcriptional condensates

In mammals, 3D genome topology has been linked to transcriptional states yet whether this link holds for other eukaryotes is unclear. Here we show that in budding yeast, Heat Shock Response (HSR) genes under the control of Heat Shock Factor (Hsf1) rapidly reposition in cells exposed to acute ethanol...

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Detalles Bibliográficos
Autores principales: Rubio, Linda S., Mohajan, Suman, Gross, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557744/
https://www.ncbi.nlm.nih.gov/pubmed/37808805
http://dx.doi.org/10.1101/2023.09.28.560064