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Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1
Phosphatidylcholine and phosphatidylethanolamine, the two most abundant phospholipids in mammalian cells, are synthesized de novo by the Kennedy pathway from choline and ethanolamine, respectively(1–6). Despite the importance of these lipids, the mechanisms that enable the cellular uptake of choline...
Autores principales: | Son, Yeeun, Kenny, Timothy C., Khan, Artem, Birsoy, Kivanç, Hite, Richard K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557757/ https://www.ncbi.nlm.nih.gov/pubmed/37808796 http://dx.doi.org/10.1101/2023.09.28.560019 |
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