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Modeling Thick Filament Activation Suggests a Molecular Basis for Force Depression

Multiscale models aiming to connect muscle’s molecular and cellular function have been difficult to develop, in part, due to a lack of self-consistent multiscale data. To address this gap, we measured the force response from single skinned rabbit psoas muscle fibers to ramp shortenings and step stre...

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Detalles Bibliográficos
Autores principales: Liu, Shuyue, Marang, Chris, Woodward, Mike, Joumaa, Venus, Leonard, Tim, Scott, Brent, Debold, Edward, Herzog, Walter, Walcott, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557758/
https://www.ncbi.nlm.nih.gov/pubmed/37808737
http://dx.doi.org/10.1101/2023.09.27.559764