Inhibition of SARS-CoV-2 Infection in Human Airway Epithelium with a Xeno-Nucleic Acid Aptamer

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BACKGROUND: SARS-CoV-2, the agent responsible for the COVID-19 pandemic, enters cells through viral spike glycoprotein binding to the cellular receptor, angiotensin-converting enzyme 2 (ACE2). Given the lack of effective antivirals targeting SARS-CoV-2, we previously utilized systematic evolution of...

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Detalles Bibliográficos
Autores principales: Razi, Niayesh, Li, Weizhong, Ignacio, Maxinne A., Loube, Jeffrey M., Agostino, Eva L., Zhu, Xiaoping, Scull, Margaret A., DeStefano, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557761/
https://www.ncbi.nlm.nih.gov/pubmed/37808754
http://dx.doi.org/10.1101/2023.09.27.559799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557761/
https://www.ncbi.nlm.nih.gov/pubmed/37808754
http://dx.doi.org/10.1101/2023.09.27.559799

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