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Adolescent oligodendrogenesis and myelination restrict experience-dependent neuronal plasticity in adult visual cortex

BACKGROUND: Developmental myelination is a protracted process in the mammalian brain. One theory for why oligodendrocytes mature so slowly posits that myelination may stabilize neuronal circuits and temper neuronal plasticity as animals age. We tested this hypothesis in the visual cortex, which has...

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Detalles Bibliográficos
Autores principales: Xin, Wendy, Kaneko, Megumi, Roth, Richard H., Zhang, Albert, Nocera, Sonia, Ding, Jun B., Stryker, Michael P., Chan, Jonah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557765/
https://www.ncbi.nlm.nih.gov/pubmed/37808666
http://dx.doi.org/10.1101/2023.09.29.560231