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Mitochondrial regulator PGC-1a in neuronal metabolism and brain aging

The brain is a high energy tissue, and the cell types of which it is comprised are distinct in function and in metabolic requirements. The transcriptional co-activator PGC-1a is a master regulator of mitochondrial function and is highly expressed in the brain; however, its cell-type specific role in...

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Detalles Bibliográficos
Autores principales: Souder, Dylan C, McGregor, Eric R, Rhoads, Timothy W, Clark, Josef P, Porter, Tiaira J, Eliceiri, Kevin, Moore, Darcie L, Puglielli, Luigi, Anderson, Rozalyn M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557769/
https://www.ncbi.nlm.nih.gov/pubmed/37808866
http://dx.doi.org/10.1101/2023.09.29.559526