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Voluntary wheel running mitigates disease in an Orai1 gain-of-function mouse model of tubular aggregate myopathy

Tubular aggregate myopathy (TAM) is an inherited skeletal muscle disease associated with progressive muscle weakness, cramps, and myalgia. Tubular aggregates (TAs) are regular arrays of highly ordered and densely packed SR straight-tubes in muscle biopsies; the extensive presence of TAs represent a...

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Detalles Bibliográficos
Autores principales: O’Connor, Thomas N., Zhao, Nan, Orciuoli, Haley M., Brasile, Alice, Pietrangelo, Laura, He, Miao, Groom, Linda, Leigh, Jennifer, Mahamed, Zahra, Liang, Chen, Malik, Sundeep, Protasi, Feliciano, Dirksen, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557777/
https://www.ncbi.nlm.nih.gov/pubmed/37808709
http://dx.doi.org/10.1101/2023.09.29.559036

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