Germline mutations and developmental mosaicism underlying EGFR-mutant lung cancer

While the development of multiple primary tumors in smokers with lung cancer can be attributed to carcinogen-induced field cancerization, the occurrence of multiple primary tumors in individuals with EGFR-mutant lung cancer who lack known environmental exposures remains unexplained. We identified te...

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Detalles Bibliográficos
Autores principales: Burr, Risa, Leshchiner, Ignaty, Costantino, Christina L, Blohmer, Martin, Sundaresan, Tilak, Cha, Justin, Seeger, Karsen, Guay, Sara, Danysh, Brian P, Gore, Ira, Jacobs, Raquel A, Slowik, Kara, Utro, Filippo, Rhrissorrakrai, Kahn, Levovitz, Chaya, Barth, Jaimie L, Dubash, Taronish, Chirn, Brian, Parida, Laxmi, Sequist, Lecia V, Lennerz, Jochen K, Mino-Kenudson, Mari, Maheswaran, Shyamala, Naxerova, Kamila, Getz, Gad, Haber, Daniel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557804/
https://www.ncbi.nlm.nih.gov/pubmed/37808694
http://dx.doi.org/10.1101/2023.09.28.23296274

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