Somatic mutations reveal hyperactive Notch signaling and racial disparities in prurigo nodularis

Prurigo nodularis (PN) is a chronic inflammatory skin disease that disproportionately affects African Americans and is characterized by pruritic skin nodules of unknown etiology. Little is known about genetic alterations in PN pathogenesis, especially relating to somatic events which are often impli...

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Detalles Bibliográficos
Autores principales: Rajeh, Ahmad, Cornman, Hannah L., Gupta, Anuj, Szeto, Mindy D., Kambala, Anusha, Oladipo, Olusola, Parthasarathy, Varsha, Deng, Junwen, Wheelan, Sarah, Pritchard, Thomas, Kwatra, Madan M., Semenov, Yevgeniy R., Gusev, Alexander, Yegnasubramanian, Srinivasan, Kwatra, Shawn G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557842/
https://www.ncbi.nlm.nih.gov/pubmed/37808834
http://dx.doi.org/10.1101/2023.09.25.23295810

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